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  1. Content type: Research

    Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated disease; however, the mechanisms that underlie the de...

    Authors: Kyoko Inagaki-Ohara, Shiki Okamoto, Kazuyo Takagi, Kumiko Saito, Seiya Arita, Lijun Tang, Tetsuji Hori, Hiroaki Kataoka, Satoshi Matsumoto and Yasuhiko Minokoshi

    Citation: Nutrition & Metabolism 2016 13:7

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  2. Content type: Research

    It is now increasingly recognized that the beneficial effects of seafood consumption is not limited to lipids and fatty acid, but that the protein part, i.e., peptides and amino acids, together with vitamins a...

    Authors: Ida-Johanne Jensen, Mari Walquist, Bjørn Liaset, Edel O. Elvevoll and Karl-Erik Eilertsen

    Citation: Nutrition & Metabolism 2016 13:8

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  3. Content type: Research

    Previous studies suggest that intake of specific bioactive compounds may have beneficial clinical effects on adipose tissue partly due to their anti-inflammatory and insulin-sensitizing properties. With the ov...

    Authors: Christel Björk, Uta Wilhelm, Susanne Mandrup, Bjørk Ditlev Larsen, Alessandra Bordoni, Per Hedén, Mikael Rydén, Peter Arner and Jurga Laurencikiene

    Citation: Nutrition & Metabolism 2016 13:4

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  4. Content type: Research

    Amino acids (AAs) are emerging as a new class of effective molecules in the etiology of obesity and diabetes mellitus. However, most investigations have focused on subjects with obesity and/or impaired glucose...

    Authors: Chisa Takashina, Ichizo Tsujino, Taku Watanabe, Shinji Sakaue, Daisuke Ikeda, Asuka Yamada, Takahiro Sato, Hiroshi Ohira, Yoshinori Otsuka, Noriko Oyama-Manabe, Yoichi M. Ito and Masaharu Nishimura

    Citation: Nutrition & Metabolism 2016 13:5

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  5. Content type: Research

    Active metabolism of peripheral blood mononuclear cells (PBMC) could suggest their suitability for metabolomics studies. This study examined whether reductions in PBMCs and plasma lipoprotein-associated phosph...

    Authors: Minjoo Kim, Gayoung Song, Miso Kang, Hye Jin Yoo, Tae-Sook Jeong, Sang-Hyun Lee and Jong Ho Lee

    Citation: Nutrition & Metabolism 2016 13:3

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  6. Content type: Research

    Resistant starch (RS) is a type of dietary fiber that can improve glucose metabolism, but its effects may be modulated by sex or baseline insulin sensitivity. This study was designed to examine the effect of h...

    Authors: Barbara A. Gower, Richard Bergman, Darko Stefanovski, Betty Darnell, Fernando Ovalle, Gordon Fisher, S. Katherine Sweatt, Holly S. Resuehr and Christine Pelkman

    Citation: Nutrition & Metabolism 2016 13:2

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    The Erratum to this article has been published in Nutrition & Metabolism 2016 13:6

  7. Content type: Research

    Microsomal triglyceride transfer protein (MTP) is essential for the assembly of lipoproteins. MTP has been shown on the surface of lipid droplets of adipocytes; however its function in adipose tissue is not we...

    Authors: Ahmed Bakillah and M. Mahmood Hussain

    Citation: Nutrition & Metabolism 2016 13:1

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  8. Content type: Research

    Better macro and micro nutrient status and their adequate intake by the athletes have great role in balancing losses associated with strenuous exercise, then for better performance. The objective of this study...

    Authors: Kifle Habte, Abdulaziz Adish, Dilnesaw Zerfu, Aweke Kebede, Tibebu Moges, Biniyam Tesfaye, Feyissa Challa and Kaleab Baye

    Citation: Nutrition & Metabolism 2015 12:62

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  9. Content type: Research

    To investigate the relationship of the neck circumference (NC) with non-alcoholic fatty liver disease (NAFLD) in non-obese Chinese population.

    Authors: Qin Li, Ningjian Wang, Bing Han, Yi Chen, Chunfang Zhu, Yingchao Chen, Fangzhen Xia, Zhen Cang, Chaoxia Zhu, Chi Chen, Hualing Zhai, Boren Jiang, Dongping Lin and Yingli Lu

    Citation: Nutrition & Metabolism 2015 12:63

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  10. Content type: Research

    Hypertriglyceridemia is a common type of dyslipidemia found in obesity. However, it is not established whether primary hyperlipidemia can predispose to obesity. Evidences have suggested that proteins primarily...

    Authors: Helena F. Raposo, Adriene A. Paiva, Larissa S. Kato and Helena C. F. de Oliveira

    Citation: Nutrition & Metabolism 2015 12:61

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  11. Content type: Research

    Excess consumption of energy-dense, high-fat Western diets contributes to the development of obesity and obesity-related disorders, such as fatty liver disease. However, not only the quantity but also the comp...

    Authors: Sharon Janssens, Mattijs M. Heemskerk, Sjoerd A. van den Berg, Natal A. van Riel, Klaas Nicolay, Ko Willems van Dijk and Jeanine J. Prompers

    Citation: Nutrition & Metabolism 2015 12:57

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  12. Content type: Research

    Physical exercise induces positive alterations in gene expression involved in the metabolism of obesity. Maternal exercise provokes adaptations soon after birth in the offspring. Here, we investigated whether ...

    Authors: Frederick Wasinski, Reury Frank Pereira Bacurau, Gabriel Rufino Estrela, Friederike Klempin, Aline Midori Arakaki, Rogerio Oliveira Batista, Fernando Francisco Pazello Mafra, Lucas Francisco Ribeiro do Nascimento, Meire Ioshie Hiyane, Lício Augusto Velloso, Niels Olsen Saraiva Câmara and Ronaldo Carvalho Araujo

    Citation: Nutrition & Metabolism 2015 12:56

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  13. Content type: Research

    N-3 polyunsaturated fatty acids (n-3 PUFAs), in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to effectively improve hepatic steatosis and insulin resistance caused by ...

    Authors: Pengfei Xu, Huan Wang, Abudurexiti Kayoumu, Mengyu Wang, Wei Huang and George Liu

    Citation: Nutrition & Metabolism 2015 12:58

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  14. Content type: Research

    Enteroendocrine cells collectively constitute our largest endocrine tissue, with serotonin (5-HT) secreting enterochromaffin (EC) cells being the largest component (~50 %). This gut-derived 5-HT has multiple p...

    Authors: Leah Zelkas, Ravi Raghupathi, Amanda L. Lumsden, Alyce M. Martin, Emily Sun, Nick J. Spencer, Richard L. Young and Damien J. Keating

    Citation: Nutrition & Metabolism 2015 12:55

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  15. Content type: Research

    Casein-free, gluten-free diets have been reported to mitigate some of the inflammatory gastrointestinal and behavioral traits associated with autism, but the mechanism for this palliative effect has not been e...

    Authors: Malav S. Trivedi, Nathaniel W. Hodgson, Stephen J. Walker, Geert Trooskens, Vineeth Nair and Richard C. Deth

    Citation: Nutrition & Metabolism 2015 12:54

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  16. Content type: Research

    Several studies in both humans and rodents have examined the use of lactoferrin as a dietary solution to weight gain and visceral fat accretion and have shown promising results in the short term (up to 7 weeks...

    Authors: Bettina McManus, Riitta Korpela, Paula O’Connor, Harriet Schellekens, John F. Cryan, Paul D. Cotter and Kanishka N. Nilaweera

    Citation: Nutrition & Metabolism 2015 12:53

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  17. Content type: Research

    The marine n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert numerous beneficial effects on health, but their potency to improve treatment of type 2 diabetic (T2D) patients remains...

    Authors: Jiri Veleba, Jan Kopecky Jr., Petra Janovska, Ondrej Kuda, Olga Horakova, Hana Malinska, Ludmila Kazdova, Olena Oliyarnyk, Vojtech Skop, Jaroslava Trnovska, Milan Hajek, Antonin Skoch, Pavel Flachs, Kristina Bardova, Martin Rossmeisl, Josune Olza…

    Citation: Nutrition & Metabolism 2015 12:52

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  18. Content type: Review

    The number of obese patients has increased annually worldwide. Therefore, there is a strong need to develop a new effective and safe anti-obesity drug. Miglitol is an alpha-glucosidase inhibitor (αGI) that is ...

    Authors: Satoru Sugimoto, Hisakazu Nakajima, Kitaro Kosaka and Hajime Hosoi

    Citation: Nutrition & Metabolism 2015 12:51

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  19. Content type: Research

    Visceral fat area (VFA), a novel sex-specific index for visceral fat obesity (VFO) might play a major role in the development of vitamin D deficiency. However, the association between VFA and vitamin D insuffi...

    Authors: Meilin Zhang, Ping Li, Yufeng Zhu, Hong Chang, Xuan Wang, Weiqiao Liu, Yuwen Zhang and Guowei Huang

    Citation: Nutrition & Metabolism 2015 12:50

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  20. Content type: Review

    Cellular metabolic changes during chronic kidney disease (CKD) may induce higher production of oxygen radicals that play a significant role in the progression of renal damage and in the onset of important como...

    Authors: Simona Granata, Alessandra Dalla Gassa, Paola Tomei, Antonio Lupo and Gianluigi Zaza

    Citation: Nutrition & Metabolism 2015 12:49

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  21. Content type: Research

    From a health promotion perspective, the use of dietary indices is preferred above single nutrients and foods to evaluate diet quality. Longitudinal research about the association between dietary indices and r...

    Authors: Evelien Mertens, Benedicte Deforche, Patrick Mullie, Johan Lefevre, Ruben Charlier, Sara Knaeps, Inge Huybrechts and Peter Clarys

    Citation: Nutrition & Metabolism 2015 12:47

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  22. Content type: Methodology

    The most common methods for obtaining human resting metabolic rate (RMR) use either a ventilated hood connected to a metabolic cart (VH_MC) or calculation by many prediction equations utilizing the person’s he...

    Authors: Russell Rising, Kathryn Whyte, Jeanine Albu and Xavier Pi-Sunyer

    Citation: Nutrition & Metabolism 2015 12:46

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  23. Content type: Research

    Although the R230C-ATP-binding cassette A1 (ABCA1) variant has been consistently associated with HDL-C levels, its association with diabetes and other metabolic parameters is unclear. Estrogen and dietary factors...

    Authors: Leonor Jacobo-Albavera, Carlos Posadas-Romero, Gilberto Vargas-Alarcón, Sandra Romero-Hidalgo, Rosalinda Posadas-Sánchez, María del Carmen González-Salazar, Alessandra Carnevale, Samuel Canizales-Quinteros, Aida Medina-Urrutia, Erika Antúnez-Argüelles and Teresa Villarreal-Molina

    Citation: Nutrition & Metabolism 2015 12:45

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  24. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD), characterized as excessive lipid accumulation within hepatocytes, is growing in prevalence. The exploitation of effective drugs for NAFLD has been proven challenging....

    Authors: Wencong Dai, Kunyuan Wang, Xinchun Zheng, Xiaohui Chen, Wenqing Zhang, Yiyue Zhang, Jinlin Hou and Li Liu

    Citation: Nutrition & Metabolism 2015 12:42

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  25. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developed countries. NAFLD encompasses a spectrum of diseases, ranging from hepatic steatosis to non-alcoholic ste...

    Authors: Rafat A. Siddiqui, Zhidong Xu, Kevin A. Harvey, Thomas M. Pavlina, Michael J. Becker and Gary P. Zaloga

    Citation: Nutrition & Metabolism 2015 12:41

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  26. Content type: Research

    Overweight in Guadeloupe is a public health matter affecting children and adults. In the present study we evaluated the metabolic profile, including serum ghrelin, leptin and adiponectin levels, in normal weig...

    Authors: Christine Rambhojan, Elodie Bouaziz-Amar, Laurent Larifla, Jacqueline Deloumeaux, Josiane Clepier, Jean Plumasseau, Jean-Marc Lacorte and Lydia Foucan

    Citation: Nutrition & Metabolism 2015 12:43

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  27. Content type: Research

    Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offsp...

    Authors: Sarah J. Glastras, Muh Geot Wong, Hui Chen, Jie Zhang, Amgad Zaky, Carol A. Pollock and Sonia Saad

    Citation: Nutrition & Metabolism 2015 12:40

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  28. Content type: Research

    It is well established that weight is an important determinant of bone health. Whereas obesity is associated with increased mortality and morbidity from diabetes and cardiovascular diseases, high body weight i...

    Authors: A. El Maghraoui, S. Sadni, A. El Maataoui, A. Majjad, A. Rezqi, Z. Ouzzif and A. Mounach

    Citation: Nutrition & Metabolism 2015 12:44

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  29. Content type: Research

    A short-term high-fat diet impairs mitochondrial function and the ability of skeletal muscle to respond to growth stimuli, but it is unknown whether such a diet alters the ability to respond to atrophy signals...

    Authors: Steven L. Roseno, Patrick R. Davis, Lance M. Bollinger, Jonathan J. S. Powell, Carol A. Witczak and Jeffrey J. Brault

    Citation: Nutrition & Metabolism 2015 12:39

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  30. Content type: Research

    Fat infiltration of the liver, muscle and pancreas is associated with insulin resistance and risk of diabetes. Weight loss reduces ectopic fat deposition and risk of diabetes, but is difficult to sustain to du...

    Authors: Nicola D. Guess, Anne Dornhorst, Nick Oliver, Jimmy D. Bell, E. Louise Thomas and Gary S. Frost

    Citation: Nutrition & Metabolism 2015 12:36

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  31. Content type: Research

    Energy restriction causes adaptations in energy expenditure (total-,TEE; resting-,REE; activity induced-,AEE).

    Authors: Stefan G. J. A. Camps, Sanne P. M. Verhoef, Nadia Roumans, Freek G. Bouwman, Edwin C. M. Mariman and Klaas R. Westerterp

    Citation: Nutrition & Metabolism 2015 12:37

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  32. Content type: Research

    Site-1 protease (S1P) is the key enzyme required for activation of the sterol regulatory element binding proteins (SREBPs) that govern lipid synthesis. While S1P has been speculated to influence plasma apoB-co...

    Authors: Debapriya Basu, Afroza Huq, Jahangir Iqbal, M. Mahmood Hussain, Xian-Cheng Jiang and Weijun Jin

    Citation: Nutrition & Metabolism 2015 12:35

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  33. Content type: Research

    Severe calorie restriction (CR) is shown to improve or even reverse β-cell dysfunction in patients with obesity and type 2 diabetes mellitus. However, whether mild to moderate CR can reverse β-cell dysfunction...

    Authors: Xiuying Gao, Dien Yan, Yinan Zhao, Hong Tao and Yingsheng Zhou

    Citation: Nutrition & Metabolism 2015 12:34

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  34. Content type: Research

    Obesity-induced hepatic lipid accumulation causes lipotoxicity, mitochondrial dysfunction, oxidative stress, and insulin resistance, and is implicated in non-alcoholic hepatic pathologies such as steatohepatit...

    Authors: Chu-Sook Kim, Yoonhee Kwon, Suck-Young Choe, Sun-Myung Hong, Hoon Yoo, Tsuyoshi Goto, Teruo Kawada, Hye-Seon Choi, Yeonsoo Joe, Hun Taeg Chung and Rina Yu

    Citation: Nutrition & Metabolism 2015 12:33

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  35. Content type: Research

    Recent studies have shown that vitamin-D intake can improve skeletal muscle function and strength in frail vitamin-D insufficient individuals. We investigated whether vitamin-D intake can improve the muscular ...

    Authors: Jakob Agergaard, Jeanette Trøstrup, Jacob Uth, Jonas Vestergard Iversen, Anders Boesen, Jesper L. Andersen, Peter Schjerling and Henning Langberg

    Citation: Nutrition & Metabolism 2015 12:32

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  36. Content type: Research

    Obesity is significant problem involving eating behavior and peripheral metabolic conditions. The effect of carbohydrate and fat restriction on appetite regulation, fibroblast growth factor 21 (FGF21) and lept...

    Authors: Lorena del Rocío Ibarra-Reynoso, Liudmila Pisarchyk, Elva Leticia Pérez-Luque, Ma. Eugenia Garay-Sevilla and Juan Manuel Malacara

    Citation: Nutrition & Metabolism 2015 12:31

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  37. Content type: Research

    Individuals with insulin resistance and resulting impaired glucose tolerance along with type 2 diabetes showed an increased prevalence of atherosclerosis. Our aim in this study was to address whether diet-indu...

    Authors: Bo Ning, Xiaoyan Wang, Ying Yu, Ahmed Bilal Waqar, Qi Yu, Tomonari Koike, Masashi Shiomi, Enqi Liu, Yifei Wang and Jianglin Fan

    Citation: Nutrition & Metabolism 2015 12:30

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  38. Content type: Research

    Both aging and obesity are related to dysregulated immune function, which may be responsible for increased risk of infection and also chronic non-infectious diseases. Dietary lipids have been shown to impact i...

    Authors: Mitra Rozati, Junaidah Barnett, Dayong Wu, Garry Handelman, Edward Saltzman, Thomas Wilson, Lijun Li, Junpeng Wang, Ascensión Marcos, José M. Ordovás, Yu-Chi Lee, Mohsen Meydani and Simin Nikbin Meydani

    Citation: Nutrition & Metabolism 2015 12:28

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  39. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is rapidly turning into the most common liver disorder worldwide. One of the strategies that has been shown to effectively improve NAFLD is regular exercise, which see...

    Authors: Sheril Alex, Andreas Boss, Arend Heerschap and Sander Kersten

    Citation: Nutrition & Metabolism 2015 12:29

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  40. Content type: Research

    Diacylglyceride acyltransferase 1 (DGAT1) is the enzyme that adds the final fatty acid on to a diacylglyceride during triglyceride (TG) synthesis. DGAT1 plays a key role in the repackaging of dietary TG into c...

    Authors: Rodney A. Velliquette, Kerry Grann, Stephen R. Missler, Jennifer Patterson, Chun Hu, Kevin W. Gellenbeck, Jeffrey D. Scholten and R. Keith Randolph

    Citation: Nutrition & Metabolism 2015 12:27

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  41. Content type: Review

    Zinc is a mineral that plays a vital role in many biological processes and plays an important role in insulin action and carbohydrate metabolism. It may also have a protective role in the prevention of atherog...

    Authors: Priyanga Ranasinghe, WS Wathurapatha, MH Ishara, R. Jayawardana, P. Galappatthy, P. Katulanda and GR Constantine

    Citation: Nutrition & Metabolism 2015 12:26

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  42. Content type: Perspective

    Intakes of high sugar-sweetened beverages (SSBs) in adults can escalate risk of metabolic syndrome (MetS); however, data of longitudinal studies in children and adolescents are lacking. In this study we assess...

    Authors: Parvin Mirmiran, Emad Yuzbashian, Golaleh Asghari, Somayeh Hosseinpour-Niazi and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2015 12:25

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  43. Content type: Research

    Body mass index (BMI) and serum 25-hydroxy vitamin D3 (25OHD) concentrations are inversely related. As BMI contains only limited information regarding body fat distribution, we aimed to analyze the cross-secti...

    Authors: A. Hannemann, B. Heinsbaek Thuesen, N. Friedrich, H. Völzke, A. Steveling, T. Ittermann, K. Hegenscheid, M. Nauck, A. Linneberg and H. Wallaschofski

    Citation: Nutrition & Metabolism 2015 12:24

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  44. Content type: Research

    Ammonia detoxification is essential for physiological well-being, and the urea cycle in liver plays a predominant role in ammonia disposal. Nobiletin (NOB), a natural dietary flavonoid, is known to exhibit var...

    Authors: Kazunari Nohara, Youngmin Shin, Noheon Park, Kwon Jeong, Baokun He, Nobuya Koike, Seung-Hee Yoo and Zheng Chen

    Citation: Nutrition & Metabolism 2015 12:23

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