Figure 1From: A C. elegans model to study human metabolic regulationThe control of energy homeostasis by adiposity and nutrient related signals. Brain receives and integrates signals from both circulatory nutrients and adiposity related hormones, such as insulin and leptin (A and B). In response, the brain maintains homeostasis of both lipid storage and metabolism by regulating food intake, and substrate metabolites (C and D).Back to article page