n | NC | NCM | HF | HFM | |
---|---|---|---|---|---|
Body weight (g) | 10-11 | 21.5 ± 0.2 | 22.2 ± 0.2 | 27.3 ± 0.4 a, b | 25.8 ± 0.4 a, b, c |
Glucose (mg/dl) | 5 | 118 ± 6.6 | 129 ± 15.4 | 282 ± 4.1 a, b | 240 ± 9.1 a, b, c |
Total cholesterol (mg/dl) | 5-7 | 62 ± 4.7 | 68 ± 4.9 | 150 ± 7.2 a, b | 141 ± 4.2 a, b |
Triglyceride (mg/dl) | 6 | 42 ± 8.4 | 45 ± 5.7 | 42 ± 4.9 | 46 ± 5.2 |
Insulin (μU/ml) | 5 | 5.3 ± 1.2 | 3.4 ± 0.5 | 12.3 ± 1.9 a, b | 6.7 ± 1.2 |
HOMA-R | 5 | 1.4 ± 0.3 | 1.1 ± 0.3 | 8.4 ± 1.3 a, b | 4.0 ± 0.7 a, b, c |
Weight of epididymal white adipose tissue (g) | 9-14 | 0.27 ± 0.02 | 0.28 ± 0.01 | 1.1 ± 0.08 a, b | 0.85 ± 0.04 a, b, c |
Weight of subcutaneous white adipose tissue (g) | 6 | 0.3 ± 0.03 | Not measured | 1.5 ± 0.15 a | 0.98 ± 0.12 a, c |
Active glucagon-like peptide1 (pg/ml) | 8-9 | 54.8 ± 7.9 | 61.1 ± 4.9 | 66 ± 7.5 | 76.9 ± 14.4 |
Concentration of miglitol (μmol/L) | 3-4 | Not measured | 0.06 ± 0.02 | Not measured | 0.26 ± 0.13 |