Table 1 Effect of MTX and glutamine on intestinal mucosal parameters

Bowel weight (mg/cm/100 g BW)

Jejunum

22.6 ± 0.9

21.3 ± 0.5

20.3 ± 0.4*

19.7 ± 1.3

Ileum

20.0 ± 0.9

19.0 ± 0.8

18.3 ± 0.8*

20.3 ± 1.1†

Mucosal weight (mg/cm/100 g BW)

Jejunum

9.7 ± 0.6

10.1 ± 0.6

6.9 ± 0.5*

8.2 ± 0.6*†

Ileum

9.0 ± 0.5

8.4 ± 0.3

7.2 ± 0.2*

9.1 ± 0.7†

Mucosal DNA (μg/cm/100 g BW)

Jejunum

4.5 ± 0.4

4.2 ± 1.4

1.6 ± 0.4*

1.6 ± 0.2*

Ileum

7.4 ± 0.8

5.5 ± 1.5

5.2 ± 0.5*

5.2 ± 0.6*

Mucosal protein (μg/cm/100 g BW)

Jejunum

160 ± 13

184 ± 30

132 ± 7*

163 ± 12†

Ileum

166 ± 8

174 ± 21

130 ± 11*

168 ± 16†