| 25% NR |
---|
 | Osteoclast | Osteoblast |
 | RANKL | OPG | RANKL | OPG |
2 Month 25% vs Control | 86 | -150 | -10 | -113 |
4 Month 25% vs Control | -16 | -160 | -232 | -160 |
6 Month 25% vs Control | 116 | -700 | -82 | -700 |
- As shown in Table 2, the percent relative difference in immunocytochemical staining in rats on a diet containing 25% NR Mg for RANKL in osteoclasts was increased at 2 and 6 months and decreased in osteoblasts. Staining for OPG was markedly decreased in both cell lines at all time points compared to control.