The levels of plasma low density lipoprotein are independent of cholesterol ester transfer protein in fish-oil fed F1B hamsters

Table 2 HDL-lipid composition of hamsters fed with various diets.

HDL-Lipids	Diet	Chol	Low Fat 5%	High Fat 20%	Statistical significance (3 way ANOVA)
					Factor	P value
Total Cholesterol (mmol/l)	FO	-	2.90 ± 0.29	2.19 ± 0.48	DT	0.0001
		+	3.96 ± 0.87	2.24 ± 0.56	CHOL	0.0020
	MIX	-	4.74 ± 0.07	5.86 ± 0.37	DT × DL	0.0001
		+	6.00 ± 1.23	6.78 ± 0.45
Free Cholesterol (mmol/l)	FO	-	0.18 ± 0.08	0.31 ± 0.07	DT	0.0001
		+	0.31 ± 0.08	0.25 ± 0.16
	MIX	-	0.60 ± 0.17	0.57 ± 0.03
		+	0.60 ± 0.17	0.59 ± 0.12
Cholesterol Ester (mmol/l)	FO	-	2.67 ± 0.29	1.88 ± 0.41	DT	0.0001
		+	3.88 ± 0.71	1.98 ± 0.49	CHOL	0.0009
	MIX	-	3.55 ± 0.61	4.34 ± 0.42	DT × DL	0.0001
		+	4.33 ± 0.80	5.34 ± 0.96
Triacylglycerol (mmol/l)	FO	-	0.32 ± 0.03	0.44 ± 0.12	DT × DL	0.0400
		+	0.39 ± 0.14	0.33 ± 0.10	DL × CHOL 0.0400
	MIX	-	0.37 ± 0.03	0.32 ± 0.03
		+	0.40 ± 0.09	0.30 ± 0.04
Phospholipids (mmol/l)	FO	-	0.57 ± 0.12	0.59 ± 0.16	DT	0.0001
		+	1.62 ± 0.43	1.27 ± 0.23	DL	0.01
	MIX	-	3.43 ± 0.26	2.91 ± 0.33	CHOL	0.0003
		+	4.20 ± 0.45	4.67 ± 0.46	DT × DL	0.0005
					DT × CHOL 0.05
					DL × CHOL 0.0007

FO, fish oil; Mix, MIX diet; Chol, cholesterol; DT, diet type; DL, diet level; CHOL, cholesterol. For details of diets and procedures, see "Materials and methods" section. Animals were fed the indicated diets for 2 weeks. All values represent means ± SD.

ISSN: 1743-7075