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Table 5 Effect of Zingiber officinale extracts on serum cholestatic markers in CCl4 treated rats

From: Zingiber officinale acts as a nutraceutical agent against liver fibrosis

Parameters

Control

CCl4 group

CCl4 treated with

ethanol extract

CCl4 treated with chloroform extract

CCl4 treated with

petroleum ether extract

CCl4 treated with silymarin

GGT

15.78 ± 1.53

(bc)

24.57 ± 3.48

(a)

16.05 ± 2.49

(c)

20.25 ± 6.22

(ab)

17.55 ± 4.57

(bc)

17.65 ± 5.46

(bc)

ALP

13.90 ± 1.41

(b)

20.38 ± 4.37

(a)

15.68 ± 5.82

(b)

14.16 ± 3.67

(b)

14.64 ± 2.30

(b)

15.68 ± 2.37

(b)

Total bilirubin

0.42 ± 0.10

(a)

1.08 ± 1.43

(b)

0.43 ± 0.09

(a)

0.45 ± 0.11

(a)

0.46 ± 0.11

(a)

0.44 ± 0.07

(a)

  1. Data are means ± SD of eight rats in each group.
  2. Data are expressed as Unit/L in GGT, ALP and mg/dL in total bilirubin.
  3. Unshared letters between groups are the significance values at p < 0.001.
  4. Statistical analysis is carried out using one way analysis of variance (ANOVA), CoStat Computer Program.