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Table 4 Correlation of Inflammatory Markers with Bone Mineral Density and Osteoporosis Biomarkers in Healthy Post-menopausal Women

From: Long-term aerobic exercise and omega-3 supplementation modulate osteoporosis through inflammatory mechanisms in post-menopausal women: a randomized, repeated measures study

 

TNF-α (pg/ml)

IL-6 (pg/ml)

PGE2 (pg/ml)

  

Regression

 

Regression

 

Regression

 

Correlation

RC

*P <

Correlation

RC

*P <

Correlation

RC

*P <

L 2 -L 4 BMD (g/cm2)

-.289

-49.8

*0.002

-.126

-25.1

0.123

-.219

-8.7

*0.005

Femoral neck BMD (g/cm2)

-0.238

-25.9

*0.049

-.097

-21.3

0.174

-.264

-6.6

*0.030

Estrogen (pg/ml)

-.283

-0.7

*0.001

.065

0.30

0.171

-.223

-0.12

*0.004

Osteocalcin (ng/ml)

-.281

-0.7

*0.001

-.157

-0.37

0.085

-.249

-0.13

*0.001

1, 25-dihydroxyvitamin D 3 (pg/ml)

-0.101

-0.1

0.147

-.048

-0.06

0.545

-.123

-0.03

0.103

CTX (ng/ml)

0.143

24.1

0.078

.119

20.9

0.137

.067

2.3

0.405

PTH (pg/ml)

0.109

0.06

0.207

.216

0.13

*0.005

.115

0.01

0.162

CT(pg/ml)

-.484

-1.7

*0.001

-.169

-0.59

*0.027

-.424

-0.29

*0.001

Ca2+ (mg/dl)

0.115

3.3

0.117

.007

0.48

0.850

.113

0.69

0.258

Phosphorus (mg/dl)

0.067

2.9

0.342

.036

1.68

0.596

.172

1.34

0.127

  1. *: P < 0.05, Adjusted for the group through the study based on mixed model.
  2. RC: Regression coefficient