Figure 5
Bcl-2, Bax, p53, cPKC and PKC-δ were differentially expressed in euploid and DS neurons which were given various treatments in the following fashion: untreated control, incubation of neurons with H 2 O 2 for 24 hours (H 2 O 2 ), incubation of neurons with γT3 (10 μM) for 24 hours (γT3), one hour of γT3 (10 μM) pre-treatment in neurons followed by H 2 O 2 incubation for 24 hours (γT3 + H 2 O 2 ), incubation of neurons with αT (10 μM) for 24 hours (αT) and one hour of αT (10 μM) pre-treatment in neurons, followed by H 2 O 2 incubation for 24 hours (αT + H 2 O 2 ). (a) Western blot of Bcl-2, Bax, p53, cPKC and PKC in DS neurons; (b) Western blot of the same proteins in euploid neurons.