A diet based on multiple functional concepts improves cardiometabolic risk parameters in healthy subjects

Nutrition & Metabolism

Table 6 Effect of CD and AD on 10-y cardiovascular risk^a

	Control Diet			Active Diet			P(A-C)^b	P(A-C; weight corrected)^c
Calculated 10-y CHD risk (%)	Week 0	Week 4	Change (%)	Week 0	Week 4	Change (%)
Framingham equation^{d, f}	5.0 ± 0.8	5.2 ± 0.8	4	5.2 ± 0.8	3.6 ± 0.6^e	-30	< 0.0001	0.0002
Reynolds score^{d, g}	6.2 ± 0.8	6.2 ± 0.8	1	6.3 ± 0.9	4.1 ± 0.6^e	-35	< 0.0001	< 0.0001

^a Values are means ± SEM.
^bP value for the comparison of changes after Active diet and Control diet.
^cP value for the comparison of changes after Active diet and Control diet, after correction for weight change.
^d The overall effect of diet was significant: P < 0.0001.
^e Significantly different from baseline (Week 0), P < 0.0001.
^f CHD risk calculated using the Framingham cardiovascular disease predictive equation [41] considering gender, age, total cholesterol, HDL-cholesterol, and smoking habits.
^g CHD risk calculated using the Reynolds risk score [42, 43] considering gender, age, total cholesterol, HDL-cholesterol, CRP and smoking habits.

ISSN: 1743-7075