Skip to main content

Table 1 Effects of theophylline (50 mg/kg bw) on body composition in rats bearing the Yoshida AH-130 ascites hepatoma

From: Theophylline is able to partially revert cachexia in tumour-bearing rats

  

Experimental group

   
 

C(n = 6)

T(n = 10)

T + TPH(n = 7)

ANOVA

    

A

B

Fat mass (g)

3.2 ± 1.1

−4.3 ± 0.5

−2.3 ± 0.7

0,000

0,045

Lean body mass (g)

23.5 ± 1.5

1.7 ± 1.7

7 ± 3

0,000

ns

Fluids (g)

0.03 ± 0.2

−0.7 ± 0.2

0.04 ± 0.3

0,034

0,025

  1. Results are expressed as the difference between day 0 (tumour inoculation) and day 7; mean ± SEM. C = non-tumour-bearing rats, T = tumour-bearing rats, T + TPH = tumour-bearing rats treated with theophylline. Statistical significance of the results by two-way analysis of variance (ANOVA); ns: non-significant differences. A (tumour effect); B (treatment effect).