Table 1 Mouse models used in this study (values are expressed as mean +/−SD; “-” indicates that data are not available)
mouse line | model | special treatment | from generation (m/f) | age (days) at section | sex (n) | mean BW at section (g) |
|---|---|---|---|---|---|---|
NMRI | fat diet FD: 18% fat | 48 | male (12) | 34.27 | ||
+/− 2.24* | ||||||
female (11) | 25.22 | |||||
+/− 1.54* | ||||||
high fat diet HDF: 80% fat | 48 | male (6) | - | |||
female (6) | - | |||||
normal fat diet ND: 3.3% fat | 48 | male (6) | 33.87 | |||
+/− 1.47 | ||||||
female (6) | 27.38 | |||||
+/− 2.41 | ||||||
DU6 | selection line: obese line | 137 (0/10) | 45 | female (10) | 64.40 | |
+/− 3.24 | ||||||
133 (5/5) | 100 | male (15) | 104.95 | |||
+/− 14.67 | ||||||
137 (10/10) | 100 | female (15) | 82.17 | |||
+/− 8.57 | ||||||
DUKs | control line: normal line | 137 (0/10) | 45 | female (10) | 25.03 | |
+/− 2.69 | ||||||
133 (5/5) | 100 | male (15) | 37.41 | |||
+/− 2.57 | ||||||
137 (10/10) | 100 | female (15) | 35.81 | |||
+/− 4.85 | ||||||
DU6i | selection line: obese line | inbreeding for the last 47 generations | 126 (12) | 45 | male (12) | 63.18 |
+/− 5.46 | ||||||
DUKsi | control line: normal line | inbreeding for the last 47 generations | 126 (12) | 45 | male (12) | 28.98 |
+/− 1.93 |