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Table 9 Estimates of fatty acid concentrations (μg/ml) in Caucasian and Asian females using hormonal contraceptives

From: Ethnicity, sex, FADS genetic variation, and hormonal contraceptive use influence delta-5- and delta-6-desaturase indices and plasma docosahexaenoic acid concentration in young Canadian adults: a cross-sectional study

Fatty acid

Caucasian females

East Asian females

non (n = 161)

HC (n = 137)

p-value

non (n = 234)

HC (n = 43)

p-value

 

μg/ml

SD

μg/ml

SD

 

μg/ml

SD

μg/ml

SD

 

18:2n6

616.5

138.1

671.1

139.0

<0.01

664.0

140.6

698.0

128.1

<0.05*

18:3n3

14.0

7.3

16.6

6.3

<0.01*

15.3

6.1

17.8

7.7

0.05

20:4n6

115.9

34.1

140.7

36.6

<0.01*

112.4

30.4

123.1

31.6

<0.01*

20:5n3

12.0

8.7

11.3

7.5

0.42

12.6

9.6

14.0

11.3

0.45

22:6n3

27.7

12.1

35.4

11.7

<0.01*

34.8

11.5

37.5

14.7

0.23

[AA/LA]

0.190

0.004

0.213

0.005

<0.01*

0.176

0.005

0.179

0.007

0.81

[DHA/ALA]

2.3

1.1

2.4

1.0

0.42

2.5

1.1

2.4

1.1

0.38

[EPA/ALA]

0.944

0.055

0.741

0.049

<0.01*

0.910

0.052

0.890

0.119

0.89

[DHA/EPA]

2.8

1.2

3.8

1.6

<0.01*

3.6

1.5

4.1

2.6

0.06

  1. Select fatty acids used as substrate and product of D5D and D6D desaturase indices. The * denotes p-values which are significant. P-values were determined using multiple linear regression models which were adjusted for BMI, age, dietary LA, ALA, EPA and DHA, % total energy from dietary fat and physical activity. Caucasian females: n = 298; East Asian Females: n = 277. Abbreviation: SD standard deviation.
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Nutrition & Metabolism

ISSN: 1743-7075

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