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Table 1 General characteristics of the experimental groups.

From: Improvement in glycemia after glucose or insulin overload in leptin-infused rats is associated with insulin-related activation of hepatic glucose metabolism

Parameter

Group

Control

Pair-fed

Leptin

Daily food intake (g)

10.11 ± 0.64

6.75 ± 0.40*

6.67 ± 0.39*

Δ body weight (g)

41.82 ± 3.97

22.50 ± 3.07**

3.12 ± 0.18**##

Glucose (mg/dl)

79.54 ± 4.62

76.70 ± 2.03

83.78 ± 3.20

Leptin (ng/ml)

4.08 ± 1.46

2.93 ± 0.38

10.62 ± 2.93**##

Insulin (ng/ml)

0.80 ± 0.13

0.76 ± 0.09

0.83 ± 0.32

Liver (g)

9.71 ± 0.49

10.12 ± 0.88

9.05 ± 1.04

Gastrocnemius (g)

0.96 ± 0.17

0.80 ± 0.12

1.19 ± 0.20#

Adipose tissue (g)

8.07 ± 0.30

5.92 ± 0.71**

3.62 ± 0.18**##

  1. Values represent mean ± SEM of 4 rats per group. Weight of adipose tissue is the sum of subcutaneous and epididymal fat pads. *p<0.05, **p<0.01 vs. control group; #p<0.05, ##p<0.01 vs. pair-fed group.