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Table 4 Hazard ratio (95 % CI) of coronary heart disease by tertiles of dietary intakes of L-arginine

From: Dietary L-arginine intake and the incidence of coronary heart disease: Tehran lipid and glucose study

 

Dietary intakes of L-arginine (n = 1237)

 

1st tertile

2nd tertile

3rd tertile

1 SD increased intakes

Total L-arginine (g/d)

<3.25

3.25–4.42

≥4.42

 

Adjustment for age and sex

Ref.

1.16 (0.59–2.29)

1.33 (0.69–2.59)

-

Multivariate model 1

Ref.

1.22 (0.61–2.41)

1.37 (0.68–2.60)

-

Multivariate model 2

Ref.

1.23 (0.61–2.43)

1.39 (0.69–2.66)

1.07 (0.63–1.81)

L-arginine from animal sources (g/d)

<1.45

1.45–1.78

≥1.87

 

Adjustment for age and sex

Ref.

1.87 (1.01–3.48)

1.32 (0.65–2.66)

-

Multivariate model 1

Ref.

1.85 (0.99–3.45)

1.29 (0.64–2.60)

-

Multivariate model 2

Ref.

1.90 (1.03–3.58)

1.46 (0.72–2.98)

1.12 (0.72–1.73)

L-arginine from plant sources (g/d)

<1.85

1.85–2.20

≥2.20

 

Adjustment for age and sex

Ref.

1.21 (0.62–2.35)

0.97 (0.50–1.89)

-

Multivariate model 1

Ref.

1.20 (0.61–2.38)

0.97 (0.48–1.92)

Multivariate model 2

Ref.

0.91 (0.51–1.62)

0.72 (0.39–1.32)

0.90 (0.51–1.61)

  1. Cox proportional hazard regression models were used
  2. Model 1: Additionally adjusted for BMI (kg/m2) and smoking status (yes/no)
  3. Model 2: Additionally adjusted for hypertension (yes/no) and diabetes mellitus (yes/no)