Fig. 3

Effect of diet and exercise training on glucose tolerance. a Change in GTT after 2 weeks of an HF diet. Fasted mice were submitted to an intraperitoneal injection of glucose (2 g/ kg b.w.). Glycemia was measured before (0) and 30, 60 and 120 min after injection. Histograms represent the area under the curve (AUC) of glycemia from 0 to 120 min. Mean ± sem. * p < 0.05, HF vs SF, t-test; # p < 0.001, HF week 2 vs HF week 0, paired t-test. b GTT at week 10. The left panel represents glycemia at the different time-points, and the right panel represents the AUC. Mean ± sem. * p ≤ 0.002, HFC vs all groups; # p < 0.05, HFT vs all groups, one-way ANOVA