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Table 1 Fasting plasma metabolic parameters

From: Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice

 

chow diet (n = 10)

HFHS diet (n = 13)

HFHS diet + EPA (n = 8)

TC (mg/dL)

67 ± 3.1

181 ± 14*

81 ± 9.6#

TG (mg/dL)

28 ± 3.7

13 ± 1.6*

12 ± 2.0

HDL-C (mg/dL)

38 ± 2.1

63 ± 3.9*

50 ± 5.5

NEFA (μEq/L)

884 ± 99

630 ± 47*

625 ± 79

ALT (IU/L)

9.4 ± 1.9

122 ± 23*

32 ± 11#

Plasma glucose (mg/dL)

106 ± 9

126 ± 4*

79 ± 5#

Insulin (ng/mL)

1.58 ± 0.02

7.06 ± 0.41*

4.15 ± 0.83#

HbAc (%)

4.58 ± 0.05

4.51 ± 0.05

4.52 ± 0.05

  1. Data are expressed as means ± SEM. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, NEFA nonesterified fatty acid, ALT alanine aminotransferase, HbA1c glycated hemoglobin, HFHS high-fat/high-sucrose, EPA eicosapentaenoic acid * P < 0.05 vs. chow diet, # P < 0.05 vs. HFHS diet