Table 3 Effects of scFOS/OF supplementation on glucose homeostasis in animals other than rodents
Animal model | Diet | FOS dose | Duration | Fasting condition | Postprandial condition | Other metabolic results | Microbiota analysis (yes/no) | Included in meta-analysis (yes/no) | References | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
G | I | Method | G | I | ||||||||
Healthy male veal calves | Whole milk + milk replacer | 10 g scFOS/d | 3 w | = | = | Lactose feeding | ↓ (after 2 h to 5 h) | ↑ (after 2 h) | ↓ lactate after lactose feeding (after 3 h and 4 h) = TG (blood) | NO | NO | [29] |
Obese male Arabian horses | Concentrate feeds and hay | 45 g scFOS/d | 6 w | = | ↓ | FSIGTT | = Sg | ↓ AIRi ↑ SI | = TG and leptin (fasting blood) | NO | NO | [28] |
Obese male Beagle dogs | 32% E fat, 44% E CHO | 1% scFOS | 6 w | = | = | Euglycemic hyperinsulinaemic clamp | ↑ glucose infusion | ↑ insulin sensitivity | ↓ HOMA-IR = TG and Chol (blood) | NO | NO | [30] |
Obese male Beagle dogs on weight-loss program | 9.5% E fat, 56.5% E CHO | 3% scFOS Vs 1% scFOS | 6 w | =a | =a | ND | ND | ND | ↓ haptoglobin | NO | NO | [31] |
Normal or obese short-hair neutered cats | 38% E fat, 8% E CHO | 2.5% mix OF/inulin | 4 w | = | = | IVGTT | = | = | = Chol, NEFA, leptin | NO | NO | [32] |