Fig. 1From: Differential ketogenic diet-induced shift in CSF lipid/carbohydrate metabolome of pediatric epilepsy patients with optimal vs. no anticonvulsant response: a pilot studyHallmark changes in ketone bodies β-hydroxybutyrate (left) and acetoacetate (middle) and glucose (right) are greater in CSF from patients with optimal response compared to those with no response. Data are scaled to one (indicated by dashed lines); means and standard errors are shown. See text for quantified β-hydroxybutyrate level. ANOVA group-x-time interactions: β-hydroxybutyrate F = 6.8, p = 0.031; acetoacetate F = 11.6, p = 0.009; glucose F = 5.8, p = 0.043. There were also significant main effects of time and patient group for each metabolite. ** p < 0.01, *** p < 0.001 compared to pre-KD; †p < 0.05, ††p < 0.01, †††p < 0.001 compared to optimal responder during KDBack to article page