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Table 2 Comparison of demographic, lifestyle characteristics and serum lipid levels of the participants

From: Weighted gene co-expression network analysis to identify key modules and hub genes related to hyperlipidaemia

Characteristic

Control (n = 462)

HCH (n = 485)

HTG (n = 474)

PHCH vs. controls

PHTG vs. controls

Male/female3

229/233

236/249

232/241

0.780

0.870

Age (years)1

57.60 ± 8.81

58.13 ± 9.69

57.10 ± 7.61

0.379

0.359

Height (cm)1

159.83 ± 8.20

160.66 ± 7.93

159.92 ± 8.11

0.114

0.771

Weight (kg)1

58.98 ± 9.90

62.66 ± 10.09

60.52 ± 11.08

1.97E−8

0.021

Body mass index (kg/m2)1

23.05 ± 3.32

24.21 ± 3.12

23.61 ± 3.67

3.59E−8

0.014

Waist circumference1

74.50 ± 8.47

78.37 ± 8.76

81.10 ± 9.21

1.00E−11

4.10E−28

Smoking, n %3

     

 Non-smoker

355

331

349

  

 ≤ 20 cigarettes/day

98

114

73

  

 > 20 cigarettes/day

9

40

52

1.73E−5

4.42E−8

Alcohol, n %3

     

 Non-drinker

377

354

363

  

 ≤ 25 g/day

45

55

44

  

 > 25 g/day

40

76

67

0.002

0.031

SBP (mmHg)1

135.49 ± 22.58

139.52 ± 22.56

141.15 ± 20.42

0.006

1.08E−4

DBP (mmHg)1

82.45 ± 12.42

84.01 ± 11.71

85.15 ± 11.72

0.047

0.001

PP (mmHg)1

53.04 ± 17.77

55.51 ± 18.19

56.00 ± 14.43

0.035

0.007

Glu (mmol/L)1

6.14 ± 1.42

6.44 ± 1.58

6.35 ± 1.32

0.002

0.015

TC (mmol/L)1

4.37 ± 0.64

5.80 ± 0.50

4.46 ± 0.37

9.42E−47

0.007

TG (mmol/L)2

0.99(0.53)

1.15(0.45)

2.30(1.03)

4.46E−9

1.69E−84

HDL-C (mmol/L)1

1.64 ± 0.48

1.48 ± 0.43

1.44 ± 0.46

2.56E−8

7.22E−11

LDL-C (mmol/L)1

2.50 ± 0.55

3.52 ± 0.80

2.79 ± 0.86

4.89E−32

1.86E−9

ApoA1 (g/L)1

1.33 ± 0.24

1.23 ± 0.25

1.25 ± 0.24

3.49E−11

4.66E−8

ApoB (g/L)1

0.98 ± 0.17

1.02 ± 0.18

1.07 ± 0.21

0.002

1.06E−11

ApoA1/ApoB1

1.39 ± 0.33

1.25 ± 0.40

1.22 ± 0.39

1.91E−8

7.62E−12

  1. SBP Systolic blood pressure; DBP Diastolic blood pressure; PP Pulse pressure; Glu Glucose; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol; Apo Apolipoprotein; TC Total cholesterol; TG Triglyceride
  2. 1Mean ± SD determined by t-test
  3. 2Median (interquartile range) tested by the Wilcoxon–Mann–Whitney test
  4. 3The rate or constituent ratio between the different groups was analyzed by the chi-square test