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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: PS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation

Fig. 2

Coimmunoprecipitation of Nur77 and TM4 and pulldown. a Coimmunoprecipitation of Nur77 and TM4. b Nur77 expression and purification. c Pulldown. d Pull down (HeLa cell). e TM4 blockade with lentivirus and its effect on the expression of Nur77. f TM4 interference and its effect on the expression of Nur77. g TM4 interference and its effect on the expression of IKK-β (western blot). h TM4 interference and its effect on the expression of IKK-β (real-time PCR). i TM4 counterregulates Nur77, IKKβ, and NF-κB

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