Fig. 3

The heatmap illustrates the differences in the umbilical cord plasma metabolome between the three groups of DC twins and MC twins. The relative concentrations of umbilical cord plasma metabolites are shown via a log2(foldchange). Red color blocks represent higher metabolites levels in dividend groups than the divisor groups, whereas blue color blocks represent lower metabolites levels in dividend groups than the divisor groups. Only the metabolites with a p-value less than 0.05 (The logistic regression adjusted for gestational age and the way of conception) were displayed. The metabolites with a significant p-value less than 0.05 and a q-value less than 0.05 were marked via a black asterisk. List of abbreviations: DC = Dichorionic; MC = Monochorionic; L = Larger twin; S = Smaller twin