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Table 2 Glycemic outcome parameters

From: The effect of the modified fat-protein unit algorithm compared with that of carbohydrate counting on postprandial glucose in adults with type-1 diabetes when consuming meals with differing macronutrient compositions: a randomized crossover trial

 

NPM-a

NPM-b

HPFM-a

HPFM-b

p value

NPM

p value

HPFM

Fasting glucose(mmol/L)

6.67 ± 0.47

6.71 ± 0.52

6.47 ± 0.40

6.16 ± 0.27

0.942

0.448

Peak glucose(mmol/L)

11.87 ± 0.74

9.33 ± 0.59

10.01 ± 0.51

9.40 ± 0.61

0.012

0.17

Time to peak glucose (min)

147.00 ± 16.38

139.00 ± 24.91

242.31 ± 21.20

153.46 ± 25.54

0.79

0.008

Mean glucose levels (mmol/L) (0-120 min)

8.98 ± 0.56

6.99 ± 0.47

7.10 ± 0.40

6.79 ± 0.33

0.008

0.501

Mean glucose levels (mmol/L) (0-240 min)

9.41 ± 0.64

6.96 ± 0.38

7.71 ± 0.38

7.23 ± 0.38

0.003

0.179

Mean glucose levels (mmol/L) (0-300 min)

9.25 ± 0.62

6.96 ± 0.34

7.94 ± 0.39

7.34 ± 0.41

0.003

0.07

Mean glucose levels (mmol/L) (120-240 min)

9.94 ± 0.77

6.94 ± 0.48

8.34 ± 0.40

7.66 ± 0.53

0.002

0.142

Mean glucose levels (mmol/L) (240–300 min)

8.67 ± 0.70

6.97 ± 0.47

8.91 ± 0.52

7.82 ± 0.69

0.038

0.026

Area under the curve(mmol/l/min)

2866.80 ± 192.51

2091.07 ± 105.63

2360.69 ± 110.59

2207.23 ± 123.95

0.001

0.166

Number of hypoglycemic events

0

5(33.3)

1(7.69)

1(7.69)

0.042

1

Time to onset of

hypoglycemic events (min)

0

123.00 ± 37.17

45.00 ± 0.00

60.00 ± 0.00

 

0

  1. NPM-a, a normal protein meal based on CC; NPM-b, a normal protein meal based on the modified FPU method; HPFM-a, a high protein-fat meal based on CC; HPFM-b, a high protein-fat meal based on the modified FPU method