Table 3 The differentially expressed genes subjected to GO and pathway analyses in Fig. 3B, C

Positive regulation of cell division

5

16.47

1.35067E-05

BTC//FGFR2//MEN1//TGFA//YBX1

Cellular macromolecule catabolic process

13

3.41

0.000105433

FAP//CTSF//SPOP//USP4//BAG6//UBA6//UBR3//SMARCC1//UBE2U//FMR1//YBX1//CIDEA//LAMP2

Cellular protein catabolic process

11

3.94

0.000107941

FAP//CTSF//SPOP//USP4//BAG6//UBA6//UBR3//SMARCC1//UBE2U//FMR1//LAMP2

Negative regulation of cellular process

34

1.86

0.000114543

CD36//CTBP1//FGFR2//MEN1//MYEF2//SPOP//YBX1//SPEN//CHCHD3//MTDH//FMR1//CBLB//MID1IP1//CDKN3//PALM//BTC//HK1//TGFA//TSC22D1//BAG6//ACVR1//FAP//ZBTB33//CIDEA//IFRD1//DYRK1A//USP4//SMARCC1//LAMP2//PTBP3//LINGO1//IFT80//GNAI1//ANAPC15

Metabolic process

61

1.42

0.000121324

CD36//CTBP1//FGFR2//MEN1//MYEF2//SPOP//YBX1//SPEN//CHCHD3//MTDH//TGFA//UBE2U//USP4//DYRK1A//FMR1//CWC22//RPL22//CBLB//UBA6//UBR3//HK1//SLC3A2//GANC//CYP2B10//GMPS//ERI3//CIDEA//SMARCC1//TSC22D1//NR2C2//ZFP37//ZSCAN12//ZBTB33//RPRD1B//PTAFR//PTBP3//NUP155//FYTTD1//ACVR1//KSR2//NAA50//DPM3//FAP//CTSF//BAG6//AMDHD1//MID1IP1//HACD2//LAMP2//PALM//NT5C3B//SLC2A4//CES1G//TSN//CDKN3//DCUN1D4//IFRD1//ZFP384//TMEM55B//GSTM3//ACSS3

Protein catabolic process

12

3.56

0.000133031

FAP//CTSF//SPOP//USP4//BAG6//UBA6//UBR3//SMARCC1//UBE2U//CBLB//LAMP2//FMR1

Macromolecule catabolic process

14

3.06

0.000174471

FAP//CTSF//SPOP//USP4//BAG6//UBA6//UBR3//SMARCC1//UBE2U//FMR1//CBLB//LAMP2//YBX1//CIDEA

Negative regulation of mRNA metabolic process

4

13.18

0.00024599

DYRK1A//PTBP3//YBX1//FMR1

Organic substance metabolic process

58

1.42

0.00027179

CD36//CTBP1//FGFR2//MEN1//MYEF2//SPOP//YBX1//SPEN//CHCHD3//MTDH//TGFA//UBE2U//USP4//DYRK1A//FMR1//CWC22//RPL22//CBLB//UBA6//UBR3//HK1//SLC3A2//GANC//CYP2B10//GMPS//ERI3//CIDEA//SMARCC1//TSC22D1//NR2C2//ZFP37//ZSCAN12//ZBTB33//RPRD1B//PTAFR//PTBP3//NUP155//FYTTD1//ACVR1//KSR2//NAA50//DPM3//FAP//CTSF//BAG6//AMDHD1//MID1IP1//HACD2//PALM//NT5C3B//SLC2A4//CES1G//TSN//DCUN1D4//IFRD1//ZFP384//TMEM55B//LAMP2

Proteolysis involved in cellular protein catabolic process

10

3.81

0.000296476

SPOP//USP4//BAG6//UBA6//UBR3//SMARCC1//UBE2U//FMR1//FAP//CTSF

Definition

Fisher-Pvalue

SelectionCounts

Enrichment_Score

Genes

ErbB signaling pathway—Mus musculus (mouse)

0.005466467

3

2.262293

BTC//CBLB//TGFA

Galactose metabolism—Mus musculus (mouse)

0.008203942

2

2.085977

GANC//HK1

Starch and sucrose metabolism—Mus musculus (mouse)

0.00870976

2

2.059994

GANC//HK1

Type II diabetes mellitus—Mus musculus (mouse)

0.01787266

2

1.747811

HK1//SLC2A4

Cocaine addiction—Mus musculus (mouse)

0.01787266

2

1.747811

GNAI1//SLC18A2

Ubiquitin mediated proteolysis—Mus musculus (mouse)

0.02099069

3

1.677973

CBLB//UBA6//UBE2U

Insulin signaling pathway—Mus musculus (mouse)

0.02179601

3

1.661623

CBLB//HK1//SLC2A4

Central carbon metabolism in cancer—Mus musculus (mouse)

0.03329764

2

1.477587

FGFR2//HK1

Hepatocellular carcinoma—Mus musculus (mouse)

0.03643455

3

1.438487

GSTM3//SMARCC1//TGFA

Adipocytokine signaling pathway—Mus musculus (mouse)

0.03702735

2

1.431477

CD36//SLC2A4