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Table 1 Baseline characteristics of the study population according to HLS#

From: Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid

Variables

Overall

HLS

P value

0–1

2

3

4–5

N

13,919

1248

3795

6101

2775

–

Age, year (mean (SD))

54.6 (13.9)

57.7 (12.3)

57.4 (13.0)

53.5(14.5)

51.7 (13.5)

 < 0.001

Female (n, %)

8171 (58.7)

122(9.8)

1580 (41.6)

4202 (68.9)

2267 (81.7)

 < 0.001

Smoking (n, %)

3951 (28.4)

1158 (92.8)

1929 (50.8)

809 (13.3)

55(2.0)

 < 0.001

Heavy drinking (n, %)

1561 (11.2)

872 (69.9)

540 (14.2)

139 (2.3)

10 (0.4)

 < 0.001

High physical activity (n, %)

3500 (25.1)

56 (4.5)

350 (9.2)

1126 (18.5)

1968 (70.9)

 < 0.001

Healthy diet (n, %)

1864 (13.4)

20 (1.6)

123 (3.2)

520 (8.5)

1201 (43.3)

 < 0.001

WC, cm (mean (SD))

79.93 (9.51)

88.12 (9.05)

84.69 (9.36)

77.39 (8.26)

75.31 (7.06)

 < 0.001

SBP, mmHg (mean (SD))

130.59 (21.89)

138.13 (21.09)

134.02 (22.02)

128.87 (21.83)

126.32 (20.64)

 < 0.001

DBP, mmHg (mean (SD))

78.87 (12.61)

83.47 (12.57)

80.21 (12.77)

77.76 (12.46)

77.44 (12.05)

 < 0.001

SUA levels, µmol/L (mean (SD))

317.44 (90.89)

380.48 (89.53)

343.27 (90.89)

302.18 (85.21)

284.84 (78.96)

 < 0.001

FPG, mmol/L (mean (SD))

4.92 (0.69)

5.09 (0.72)

4.92 (0.71)

4.89 (0.67)

4.92 (0.67)

 < 0.001

TG, mmol/L (median [IQR])

1.23 [0.87, 1.81]

1.35 [0.95, 2.05]

1.35 [0.95, 2.01]

1.19 [0.85, 1.73]

1.13 [0.82, 1.65]

 < 0.001

HDL.C, mmol/L (mean (SD))

1.42 (0.37)

1.39 (0.38)

1.37 (0.36)

1.44 (0.36)

1.48 (0.38)

 < 0.001

Hypertension (n, %)

5401 (39.5)

682 (55.5)

1712 (45.9)

2121 (35.4)

886 (32.6)

 < 0.001

Family history of hypertension (n, %)

3997 (28.7)

452 (36.2)

1007 (26.5)

1715 (28.1)

823 (29.7)

 < 0.001

Family history of diabetes (n, %)

713 (5.1)

70 (5.6)

170 (4.5)

313 (5.1)

160 (5.8)

0.102

Use of anti-hypertensive medication (n, %)

1002 (7.2)

136 (10.9)

352 (9.3)

387 (6.3)

127 (4.6)

 < 0.001

Use of lipid-lowing medication (n, %)

107 (0.8)

15 (1.2)

34 (0.9)

40 (0.7)

18 (0.6)

0.143

  1. #HLS: healthy lifestyle scores, numbers of healthy lifestyle behaviors including healthy WC (< 90 cm for men, or < 85 cm for women), never smoking, high physical activity (top sex-specific quartile of MET-h/week, cut-off values are 321.9 MET-h/week for male and 243.6 for female.), healthy diet (≥ 2 dietary components at ideal levels), and moderate alcohol intake (< 3 times/week)