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Table 2 Adjusted HR for association between HLS and T2DM

From: Healthy lifestyle scores associate with incidence of type 2 diabetes mediated by uric acid

HLS

Number of T2DM

Person-year

Incidence per 1000 person-years

Model 1

Model 2

   

HR (95% CI)

P

HR (95% CI)

P

0–1

82

11,972.06

6.85

1.00

–

1.00

–

2

217

36,149.31

6.00

0.77 (0.59, 1.01)

0.051

0.84 (0.64, 1.10)

0.255

3

271

58,572.80

4.63

0.61 (0.47, 0.81)

 < 0.001

0.73 (0.55, 0.96)

0.026

4–5

75

27,382.26

2.74

0.36 (0.26, 0.51)

 < 0.001

0.40 (0.28, 0.57)

 < 0.001

P-trend

–

–

–

–

 < 0.001

–

 < 0.001

Per score

–

–

–

0.74 (0.67, 0.81)

 < 0.001

0.77 (0.71, 0.85)

 < 0.001

PAR% (%, 95% CI) #

–

–

–

–

–

43.24 (30.02,56.46)

–

  1. Model 1: adjusted for age, sex, family history of diabetes, family history of hypertension, prevalence of hypertension, use of anti-hypertensive medication, and use of lipid-lowing medication
  2. Model 2: Model1 + TG (mmol/L), HDL-C (mmol/L), and FPG (mmol/L)
  3. #PAR% was calculated to estimate the percentage of T2DM that would have been prevented if all participants had been in more than 4 healthy lifestyle behaviors
  4. HR, hazard ratio; HLS, healthy lifestyle scores; T2DM, type 2 diabetes mellitus; CI, confidence interval; PAR%, population-attributable risk percent