Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis

Nutrition & Metabolism

Table 1 The ratio of kidney weight to body weight on postnatal days 0 and 7 in the control and IUGR groups

Group	n	Body weight (g)	Kidney weight (g)	Kidney: body weight (%)
Postnatal day 0
Control	12	6.40 ± 0.56	0.072 ± 0.012	1.13 ± 0.20
IUGR	8	5.38 ± 0.88^**	0.048 ± 0.016^**	0.91 ± 0.32†
Postnatal day 7
Control	12	16.90 ± 1.39	0.223 ± 0.025	1.33 ± 0.19
IUGR	8	14.50 ± 0.55^***	0.189 ± 0.016^**	1.31 ± 0.13

On postnatal day 0, the sham-operated and UPI-induced dams had three and four litters, respectively. On postnatal day 7, the offspring number was reassigned to three and two in the sham-operated and UPI-induced groups, respectively. Values are means ± standard deviations. ^**p < 0.01, ^***p < 0.001 versus control group at each postnatal age. †p = 0.078 versus control group on postnatal day 0. IUGR: intrauterine growth restriction

ISSN: 1743-7075