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Table 2 Ten compounds significantly different between the IUGR and control groups in the renal cortex of rats (n = 6) as determined through univariate analysis with false discovery rate correction (q < 0.05) on postnatal day 7

From: Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis

Compound

p value

q value

Identification

IUGR/control

P1

0.0001

0.0019

Taurine

Down

P2

0.0006

0.0238

PE(18:3(6Z,9Z,12Z)/P-18:1(9Z))

Down

P3

0.0011

0.0248

N-acetylglutamine

Up

P4

0.0011

0.0248

(2S)-2-hydroxy-2-(propan-2-yl)butanedioylcarnitine

Up

P5

0.0011

0.0248

PG(i-12:0/5-iso PGF2VI), PG(5-iso PGF2VI/i-12:0)

Up

P6

0.0012

0.0248

L-cysteine, D-cysteine

Down

P7

0.0012

0.0248

PC(15:0/18:2(9Z,12Z))

Down

P8

0.0014

0.0268

PS(DiMe(13,5)/MonoMe(13,5)), PS(MonoMe(13,5)/DiMe(13,5))

Up

P9

0.0015

0.0268

Cortisol, 18-hydroxycorticosterone, 17a,21-dihydroxy-5b-pregnane-3,11,20-trione

Up

P10

0.0024

0.0384

PE(22:0/PGJ2), PE(PGJ2/22:0)

Up

  1. The ratio of IUGR to controls is either greater than 1 or less than 1, expressed as up or down. Compounds are numbered as P1–P10