Skip to main content
Fig. 3 | Nutrition & Metabolism

Fig. 3

From: Amelioration of Atherosclerosis by lycopene is linked to the modulation of gut microbiota dysbiosis and related gut-heart axis activation in high-fat diet-fed ApoE−/− mice

Fig. 3

Lycopene supplementation modulated the relative abundance of gut microbiota in HFD-fed ApoE−/− mice. ApoE−/− mice were fed a low-fat diet, a high-fat diet supplemented with or without 0.1% lycopene (w/w) for 19 weeks. (A, C, D, F) Different expression of relative abundance of gut microbiota in three groups at phylum level. (E) The ratio of Firmicutes/Bacteroides in three groups. Data was analyzed by R software and presented as the mean ± SD (n = 6 per group); ap < 0.05 compared with the control group; bp < 0.05 compared with the high-fat diet group. (B, G, H) Different expressions of relative abundance of gut microbiota in three groups at genus level. Data was analyzed by R software and presented as the mean ± SD (n = 6 per group); ap < 0.05 compared with the control group; bp < 0.05 compared with the high-fat diet group. HFD, high-fat diet; LY, lycopene. For species difference analysis and abundance calculation, the reshape2, ggplot2, ggprism, and plyr packages of R software were used

Back to article page