Table 2 Basic parameters and biochemical markers measured in ApoE^−/− mice

Basic parameters

Food intake (g/d)

Initial body weight (g)

Final body weight (g)

Body weight gain (g)

4.00 ± 0.03

22.46 ± 0.99

31.95 ± 1.49

9.49 ± 1.63

4.02 ± 0.12

21.94 ± 0.87

33.59 ± 3.34

11.65 ± 3.39

4.01 ± 0.06

21.95 ± 1.02

30.76 ± 3.97

8.81 ± 3.73

Heart (standardize to body mass)

0.37 ± 0.32

0.34 ± 0.33

0.38 ± 0.33

Aorta (standardize to body mass)

0.54 ± 0.38

0.45 ± 0.32

0.61 ± 0.32

TC (mmol/L)

11.18 ± 3.53^c

40.06 ± 9.49^c

25.39 ± 4.27^c

TG (mmol/L)

1.11 ± 0.46

2.91 ± 0.83^a

2.57 ± 1.15

LDL-C (mmol/L)

21.3 ± 2.82

39.3 ± 3.07^a

22.61 ± 2.05^b

HDL-C (mmol/L)

14.43 ± 1.21^c

4.84 ± 1.33^c

10.69 ± 1.01^c

Serum biochemical marker

TNF-α(pg/ml)

60.23 ± 11.87

85.04 ± 33.34^a

41.00 ± 9.89^b

MCP-1(pg/ml)

93.37 ± 16.87

114.87 ± 20.63^a

97.87 ± 8.52^b

IL-6(pg/ml)

56.38 ± 11.35

93.82 ± 32.34^a

71.00 ± 15.85^b

IL-1β(pg/ml)

65.23 ± 11.84

87.61 ± 24.89^a

66.02 ± 7.56^b