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Fig. 3 | Nutrition & Metabolism

Fig. 3

From: Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease

Fig. 3

Changes of liver index, histopathological structure and NAS after feeding different diets in mice. C57BL/6 mice were randomly divided into three groups, including control (C), high fat diet (HFD), high fat and riboflavin deficient diet (HFRD), and fed for 30 days. A Liver weight as a percentage of body weight. B–C Serum ALT and AST levels were determined using corresponding kits. D Serum and liver TG and TC levels were determined using corresponding kits. E Anatomical view of the liver. F Representative pictures of HE (20×) and Oil Red O (40×) stained liver sections. G NAFLD activity score, 6 mice per group. Data are expressed as means ± SD. *P < 0.05 versus C; #P < 0.05 versus HFD

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Nutrition & Metabolism

ISSN: 1743-7075

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