Fig. 4

Coenzyme Q₁₀ reversed the HFD-induced suppression of mitochondrial fusion in aortic PVAT. Representative gel and densitometric analyses of A OPA1, B MFN1, and C MFN2 in the aortic PVAT of the ND, HFD and HFD + Q groups at the age of 20 weeks. Values are the mean ± SEM, n = 9 for each group. *P < 0.05, **P < 0.01 versus the ND group and ^#P < 0.05 versus the HFD group in the post hoc Tukey’s multiple range test. ND, normal diet, HFD, high fructose diet, HFD + Q, HFD with coenzyme Q₁₀. OPA1, mitochondrial Dynamin-Like GTPase, MFN, mitofusin, β-actin as the internal control