Fig. 5
Coenzyme Q10 reversed HFD-induced mitochondrial fission in aortic PVAT. Representative gel and densitometric analyses of A FIS, B DRP1, C p-DRP1 and D the ratio of p-DRP1/DPR1 in the aortic PVAT of the ND, HFD and HFD + Q groups at the age of 20 weeks. Values are the mean ± SEM, n = 8 for each group. *P < 0.05, **P < 0.01, ***P < 0.001 versus the ND group and #P < 0.05 versus the HFD group in the post hoc Tukey’s multiple range test. ND, normal diet, HFD, high fructose diet, HFD + Q, HFD with coenzyme Q10. FIS1, mitochondrial fission 1 protein, DRP1, dynamin-related protein 1, p-DRP1, phospho-DRP1, β-actin as the internal control