Fig. 6

Coenzyme Q₁₀ treatment reversed the HFD-induced increase in fibrotic and calcification proteins in aortic PVAT. Representative gel and densitometric analyses of A α-SMA and B osteocalcin in the aortic PVAT of the ND, HFD and HFD + Q groups at the age of 20 weeks. Values are the mean ± SEM, n = 4 for each group. *P < 0.05, **P < 0.01 versus the ND group and ^##P < 0.01, ^###P < 0.001 versus the HFD group in the post hoc Tukey’s multiple range test. ND, normal diet, HFD, high fructose diet, HFD + Q, HFD with coenzyme Q₁₀. α-SMA, α-smooth muscle actin, β-actin as the internal control