Figure 1From: Timing of supplementation of selenium and isoflavones determines prostate cancer risk factor reduction in ratsWeight gain of pups and breeders. A. Body weights of pups. Symbols and error bars represent means ± SEM for each dietary group at each time point. N = 23–24 rats/group up to 35 days, N = 15–16 rats/group from 35–100 days, and from 100–200 days N = 8 rats/group. By ANOVA, diet was a significant determinant (p < 0.005) of body weight as early as 35 days, which significance continued until the end of the study. At 35 days and 200 days means not sharing a common superscript are significantly (p < 0.05) different by Fisher's pairwise comparisons. The main effect of isoflavones was statistically significant at each time point (p = 0.047 and p = 0.001 at 35 days and 200 days, respectively) while the main effect of Se was not. B. Body weights of breeders. N = 3–4 for each dietary group at each time point. Symbols and error bars represent means ± SEM for each dietary group at each time point. There were no statistically significant effects of diet on body weight at any time point. Abbreviations: Adequate (0.33–0.45 mg/kg diet) Se, Adq. Se; High (3.33–3.45 mg/kg) Se, High Se; Low (10 mg/kg) isoflavones, Low IF; High (600 mg/kg) isoflavones, High IF.Back to article page