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Table 3 Plasma concentrations of liver enzymes, lipids, total protein, bilirubin and urea from the control and the different groups

From: Folic acid and melatonin ameliorate carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats

Parameters

Control group

CCL4

Me

CCL4+Me

Fo

CCL4+Fo

CCL4+Me + Fo

ALP (U/L)

232.6 ± 33.5

418.3* ± 67

238.6 ± 62

279.1 ± 34

234.7 ± 43

267.3 ± 61

228 ± 35

ALT (U/L)

27 ± 3.8

369* ± 106

29 ± 3.0

293.5* ± 34

22.7 ± 1.1

205.5* ± 77

156.5* ± 62

AST (U/L)

48.7 ± 4.0

369* ± 91

42.1 ± 4.8

251* ± 48

41 ± 7.2

288.7* ± 112

237.7* ± 71

LDH (U/L)

192.3 ± 63

576* ± 221

165.3 ± 47

317.3 ± 110

178.6 ± 43

363.3 ± 130

337.5 ± 143

Cholesterol (mg/100 ml)

57.7 ± 8.0

87* ± 14

53 ± 6.0

59 ± 9.0

61 ± 5.0

76* ± 14

57 ± 8.6

LDL-C (mg/100 ml)

33 ± 6.6

50* ± 15

37 ± 6.0

38 ± 2.3

36 ± 5.7

44* ± 5.0

36 ± 6.0

HDL (mg/100 ml)

31 ± 5.5

10* ± 4.9

32 ± 5.6

16* ± 7.0

30 ± 5.4

24 ± 7.3

27 ± 6.3

Triglycerides (mg/100 ml)

66 ± 4.3

125* ± 10

51 ± 6.0

82* ± 7.0

65 ± 6.2

70 ± 6.2

66 ± 3.2

Plasma Protein g/100 ml

7.7 ± 0.6

5.5* ± 0.5

7.3 ± 0.9

5.8* ± 0.35

6.7 ± 0.7

5.7* ± 0.7

6.7 ± 0.7

Bilirubin Mg/100 ml

0.246 ± 0.08

0.468 ± 0.17

0.226 ± 0.04

0.324 ± 0.06

0.266 ± 0.06

0.42* ± 0.1

0.355 ± 0.07

Urea Mg/100 ml

40.6 ± 7.3

55.5* ± 10

33.6 ± 5.9

55* ± 9.5

50.8 ± 7.0

48.5 ± 3.0

37.6 ± 5.4

  1. The results are expressed as the M ± SD. * shows a statistically significant difference (P < 0.05) in the pairwise comparison between a treatment group and the control.