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Table 3 Plasma concentrations of liver enzymes, lipids, total protein, bilirubin and urea from the control and the different groups

From: Folic acid and melatonin ameliorate carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats

Parameters Control group CCL4 Me CCL4+Me Fo CCL4+Fo CCL4+Me + Fo
ALP (U/L) 232.6 ± 33.5 418.3* ± 67 238.6 ± 62 279.1 ± 34 234.7 ± 43 267.3 ± 61 228 ± 35
ALT (U/L) 27 ± 3.8 369* ± 106 29 ± 3.0 293.5* ± 34 22.7 ± 1.1 205.5* ± 77 156.5* ± 62
AST (U/L) 48.7 ± 4.0 369* ± 91 42.1 ± 4.8 251* ± 48 41 ± 7.2 288.7* ± 112 237.7* ± 71
LDH (U/L) 192.3 ± 63 576* ± 221 165.3 ± 47 317.3 ± 110 178.6 ± 43 363.3 ± 130 337.5 ± 143
Cholesterol (mg/100 ml) 57.7 ± 8.0 87* ± 14 53 ± 6.0 59 ± 9.0 61 ± 5.0 76* ± 14 57 ± 8.6
LDL-C (mg/100 ml) 33 ± 6.6 50* ± 15 37 ± 6.0 38 ± 2.3 36 ± 5.7 44* ± 5.0 36 ± 6.0
HDL (mg/100 ml) 31 ± 5.5 10* ± 4.9 32 ± 5.6 16* ± 7.0 30 ± 5.4 24 ± 7.3 27 ± 6.3
Triglycerides (mg/100 ml) 66 ± 4.3 125* ± 10 51 ± 6.0 82* ± 7.0 65 ± 6.2 70 ± 6.2 66 ± 3.2
Plasma Protein g/100 ml 7.7 ± 0.6 5.5* ± 0.5 7.3 ± 0.9 5.8* ± 0.35 6.7 ± 0.7 5.7* ± 0.7 6.7 ± 0.7
Bilirubin Mg/100 ml 0.246 ± 0.08 0.468 ± 0.17 0.226 ± 0.04 0.324 ± 0.06 0.266 ± 0.06 0.42* ± 0.1 0.355 ± 0.07
Urea Mg/100 ml 40.6 ± 7.3 55.5* ± 10 33.6 ± 5.9 55* ± 9.5 50.8 ± 7.0 48.5 ± 3.0 37.6 ± 5.4
  1. The results are expressed as the M ± SD. * shows a statistically significant difference (P < 0.05) in the pairwise comparison between a treatment group and the control.