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  1. Content type: Research

    As reported previously by our group, medium-chain triglycerides can ameliorate atherosclerosis. Given that TLR4 is closely related to atherosclerosis, we hypothesized herein that caprylic acid (C8:0) would sup...

    Authors: Xinsheng Zhang, Changyong Xue, Qing Xu, Yong Zhang, Huizi Li, Feng Li, Yinghua Liu and Changjiang Guo

    Citation: Nutrition & Metabolism 2019 16:40

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  2. Content type: Research

    Long non-coding RNAs (lncRNAs) are involved in numerous physiological functions. Yet, their mechanisms in coronary artery disease (CAD) are not well understood.

    Authors: Liu Miao, Rui-Xing Yin, Qing-Hui Zhang, Xi-Jiang Hu, Feng Huang, Wu-Xian Chen, Xiao-Li Cao and Jin-Zhen Wu

    Citation: Nutrition & Metabolism 2019 16:39

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  3. Content type: Research

    The incidence of metabolic syndrome linked to dyslipidemia and insulin resistance has increased; thus, studies must be conducted to elucidate this phenomenon. The present study aimed to investigate the protect...

    Authors: Oeuk Jeong and Hyun-Sook Kim

    Citation: Nutrition & Metabolism 2019 16:38

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  4. Content type: Research

    Proliferative diabetic retinopathy (PDR), a sight-threatening retinopathy, is the leading cause of irreversible blindness in adults. Despite strict control of systemic risk factors, a fraction of patients with...

    Authors: Xiao-Rong Zhu, Fang-yuan Yang, Jing Lu, Hui-rong Zhang, Ran Sun, Jian-Bo Zhou and Jin-Kui Yang

    Citation: Nutrition & Metabolism 2019 16:37

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  5. Content type: Research

    High levels circulating saturated fatty acids are associated with diabetes, obesity and hyperlipidemia. In heart, the accumulation of saturated fatty acids has been determined to play a role in the development...

    Authors: Kuen-Ming Wu, Yuan-Man Hsu, Mei-Chin Ying, Fuu-Jen Tsai, Chang-Hai Tsai, Jing-Gung Chung, Jai-Sing Yang, Chih-Hsin Tang, Li-Yi Cheng, Po-Hua Su, Vijaya Padma Viswanadha, Wei-Wen Kuo and Chih-Yang Huang

    Citation: Nutrition & Metabolism 2019 16:36

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  6. Content type: Research

    Blueberry is rich in bioactive substances and possesses powerful antioxidant potential, which can protect against oxidant-induced and inflammatory cell damage and cytotoxicity. The aim of this study was to det...

    Authors: Weixiang Liu, Yiping Mao, Jacob Schoenborn, Zhihong Wang, Guiliang Tang and Xiaoqing Tang

    Citation: Nutrition & Metabolism 2019 16:34

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  7. Content type: Review

    Cutaneous malignant melanoma is a heterogeneous disease, being the consequence of specific genetic alterations along several molecular pathways. Despite the increased knowledge about the biology and pathogenes...

    Authors: Maria Neve Ombra, Panagiotis Paliogiannis, Luigia Stefania Stucci, Maria Colombino, Milena Casula, Maria Cristina Sini, Antonella Manca, Grazia Palomba, Ignazio Stanganelli, Mario Mandalà, Sara Gandini, Amelia Lissia, Valentina Doneddu, Antonio Cossu and Giuseppe Palmieri

    Citation: Nutrition & Metabolism 2019 16:33

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  8. Content type: Research

    Adipogenesis, the process of preadipocyte differentiation to mature adipocytes accompanied by accumulation of intracytoplasmic lipid droplets, is regulated by various genetic and environmental factors, and clo...

    Authors: Yusuke Ando, Fumiaki Sato, Hazuki Fukunaga, Yusuke Iwasaki, Yoshihiko Chiba, Masahiko Tebakari, Yuki Daigo, Junichi Kawashima and Junzo Kamei

    Citation: Nutrition & Metabolism 2019 16:32

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  9. Content type: Research

    Obesity increases the risk of metabolic dysfunction such as dyslipidemia, hypertension, and fatty liver. Physcion (PY) is an anthraquinone that reportedly has anti-inflammatory and anti-bacterial properties. H...

    Authors: Seon-Jeong Lee, Su-Jung Cho, Eun-Young Kwon and Myung-Sook Choi

    Citation: Nutrition & Metabolism 2019 16:31

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  10. Content type: Research

    Several biomarkers are used to measure iron deficiency (ID) during pregnancy, but the prevalence of ID and its association with adverse birth outcomes shows inconsistent results. The aim of this study was to e...

    Authors: Xiaosong Yuan, Huiwen Hu, Ming Zhang, Wei Long, Jianbing Liu, Jian Jiang and Bin Yu

    Citation: Nutrition & Metabolism 2019 16:30

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  11. Content type: Research

    It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in thr...

    Authors: Iva Mandic, Mavra Ahmed, Shawn Rhind, Len Goodman, Mary L’Abbe and Ira Jacobs

    Citation: Nutrition & Metabolism 2019 16:29

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  12. Content type: Research

    This study aimed to assess the potential effects of long-term intake of caffeine and habitual consumption of coffee and tea on the occurrence of cardio-renal events among an Iranian population with low coffee ...

    Authors: Zahra Gaeini, Zahra Bahadoran, Parvin Mirmiran and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2019 16:28

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  13. Content type: Research

    Reprogramming of fast-to-slow myofiber switch can improve endurance capacity and alleviate fatigue. Accumulating evidence suggests that a muscle-specific microRNA, miR-499 plays a crucial role in myofiber type...

    Authors: Luting Wu, Li Ran, Hedong Lang, Min Zhou, Li Yu, Long Yi, Jundong Zhu, Lei Liu and Mantian Mi

    Citation: Nutrition & Metabolism 2019 16:27

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  14. Content type: Research

    Prolonged over-consumption of a high-fat diet (HFD) commonly leads to obesity and insulin resistance. However, even 3 days of HFD consumption has been linked to inflammation within the key homeostatic brain re...

    Authors: Fiona H. McLean, Fiona M. Campbell, Rosamund F. Langston, Domenico Sergi, Cibell Resch, Christine Grant, Amanda C. Morris, Claus D. Mayer and Lynda M. Williams

    Citation: Nutrition & Metabolism 2019 16:26

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  15. Content type: Research

    Myricetin, a major flavonoid found in several foods including berries, grapes and wine, exhibited strong antioxidant potency, yet the effect on atherosclerosis is not fully understood. In this study, we examin...

    Authors: Zhe Meng, Mengyu Wang, Junhui Xing, Yuzhou Liu and Haiyu Li

    Citation: Nutrition & Metabolism 2019 16:25

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  16. Content type: Research

    Consumption of diet high in soy products is suggested to contribute to lower prostate cancer incidence in Asian men. But little has been known about the influences of dietary patterns on gut microbiota and mic...

    Authors: Yufei Liu, Xiaobo Wu and Haowen Jiang

    Citation: Nutrition & Metabolism 2019 16:24

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  17. Content type: Research

    The process of atherosclerosis begins early in childhood and usually remains asymptomatic until later in life. Carotid intima-media thickness (cIMT) as a marker of subclinical atherosclerosis could identify ea...

    Authors: Maryam Aghayan, Golaleh Asghari, Emad Yuzbashian, Pooneh Dehghan, Hossein Khadem Haghighian, Parvin Mirmiran and Maryam Javadi

    Citation: Nutrition & Metabolism 2019 16:23

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  18. Content type: Research

    Chronic inflammation and metabolic dysregulation may eventually cause tissue damage in obesity-related diseases such as type 2 diabetes. The effects of SIRT1 on integration of metabolism and inflammation may p...

    Authors: Hung-Wen Liu, Hao-Han Kao and Chi-Hang Wu

    Citation: Nutrition & Metabolism 2019 16:22

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  19. Content type: Research

    Differences in total body and regional adiposity according to sex are observed from an early age, but these differences become more evident after puberty due to hormonal changes. We aimed to assess the evoluti...

    Authors: Silvana Paiva Orlandi, Leonardo Pozza Santos, Ana Maria Baptista Menezes, Fernando C. Wehrmeister, Helen Gonçalves and Maria Cecília Formoso Assunção

    Citation: Nutrition & Metabolism 2019 16:21

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  20. Content type: Research

    Maternal undernutrition programs fetal energy homeostasis and increases the risk of metabolic disorders later in life. This study aimed to identify the signs of hepatic metabolic programming in utero and durin...

    Authors: Xiaoling Zhou, Hong Yang, Qiongxian Yan, Ao Ren, Zhiwei Kong, Shaoxun Tang, Xuefeng Han, Zhiliang Tan and Abdelfattah Z. M. Salem

    Citation: Nutrition & Metabolism 2019 16:20

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  21. Content type: Research

    Maternal riboflavin deficiency (RD) induces embryonic death in poultry. The underlying mechanisms, however, remain to be established and an overview of molecular alterations at the protein level is still lacki...

    Authors: Jing Tang, Jian Hu, Ming Xue, Zhanbao Guo, Ming Xie, Bo Zhang, Zhengkui Zhou, Wei Huang and Shuisheng Hou

    Citation: Nutrition & Metabolism 2019 16:19

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  22. Content type: Research

    Gut derived toxins such as p-cresol, p-cresyl sulfate (pCS) and indoxyl sulfate (IS), which belong to protein-bound uremic toxins that promote development of fibrosis inflammatory state associated with chronic...

    Authors: Hamid Tayebi Khosroshahi, Behzad Abedi, Morteza Ghojazadeh, Azam Samadi and Abolghasem Jouyban

    Citation: Nutrition & Metabolism 2019 16:18

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  23. Content type: Research

    To investigate the influences of exercise on the levels of chemerin and its receptor chemokine-like receptor (CMKLR1) in the peripheral metabolic organs of obesity and diabetes rats, and whether the mechanism ...

    Authors: Xiaojing Lin, Yanan Yang, Jing Qu and Xiaohui Wang

    Citation: Nutrition & Metabolism 2019 16:17

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  24. Content type: Research

    Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, a...

    Authors: Yazan Ranneh, Abdah Md Akim, Hasiah Ab Hamid, Huzwah Khazaai, Abdulmannan Fadel and Ayman M. Mahmoud

    Citation: Nutrition & Metabolism 2019 16:15

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  25. Content type: Research

    Adiponectin exerts several beneficial cardiovascular effects, however their specific molecular mechanisms require additional understanding. This study investigated the mechanisms of adiponectin action in the h...

    Authors: Amy Botta, Ying Liu, Sivaporn Wannaiampikul, Rungsunn Tungtrongchitr, Keith Dadson, Tae-Sik Park and Gary Sweeney

    Citation: Nutrition & Metabolism 2019 16:14

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  26. Content type: Research

    Iron is a critical component of metabolic homeostasis, but consumption of dietary iron has increased dramatically in the last 30 years, corresponding with the rise of metabolic disease. While the link between ...

    Authors: Mario A. Miranda, Celine L. St Pierre, Juan F. Macias-Velasco, Huyen Anh Nguyen, Heather Schmidt, Lucian T. Agnello, Jessica P. Wayhart and Heather A. Lawson

    Citation: Nutrition & Metabolism 2019 16:13

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  27. Content type: Research

    Oil tea is a type of traditional tea beverage used for treating various ailments in minority population in Guangxi, China. Our previous study showed oil tea improved glucose and lipid levels in type 2 diabetic...

    Authors: Qiantu Hu, Huafeng Chen, Yanli Zuo, Qin He, Xuan He, Steve Simpson Jr, Wei Huang, Hui Yang, Haiying Zhang and Rui Lin

    Citation: Nutrition & Metabolism 2019 16:12

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  28. Content type: Research

    Catch-up growth in adult (CUGA) is characterized by visceral fat accumulation, ectopic lipid deposition and insulin resistance (IR). Here, we investigated the determinants of these pathophysiological consequen...

    Authors: Yan Li, Shan Yu, Lulu Chen, Xiang Hu, Juan Zheng and Xiuling Deng

    Citation: Nutrition & Metabolism 2019 16:11

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  29. Content type: Research

    Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resveratrol (...

    Authors: Jining Yang, Xi Zhou, Xianglong Zeng, Ou Hu, Long Yi and Mantian Mi

    Citation: Nutrition & Metabolism 2019 16:9

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  30. Content type: Research

    Since lifestyle changes are main therapies for non-alcoholic fatty liver disease (NAFLD), changing dietary components (nutritional or bioactive) may play a parallel important role. Few studies have assessed th...

    Authors: Seyed Ali Jazayeri-Tehrani, Seyed Mahdi Rezayat, Siavash Mansouri, Mostafa Qorbani, Seyed Moayed Alavian, Milad Daneshi-Maskooni and Mohammad-Javad Hosseinzadeh-Attar

    Citation: Nutrition & Metabolism 2019 16:8

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  31. Content type: Research

    Small dense LDL cholesterol (sdLDL-c) has been established to be highly associated with metabolic disorder. However, the relationship between circulating sdLDL-c and the presence of metabolic syndrome (MetS) h...

    Authors: Jiahua Fan, Yangqing Liu, Songping Yin, Nixuan Chen, Xinxiu Bai, Qiuyi Ke, Jia Shen and Min Xia

    Citation: Nutrition & Metabolism 2019 16:7

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  32. Content type: Research

    Obesity has become a public health concern worldwide because it is linked to numerous metabolic disorders, such as hyperlipidemia, hypertension and cardiovascular disease. Therefore, there is an urgent need to...

    Authors: Licong Yang, Yan Zhao, Yongfang Pan, Dongming Li and Guodong Zheng

    Citation: Nutrition & Metabolism 2019 16:6

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  33. Content type: Research

    The GC haplotype of the vitamin D binding protein (encoded by the GC gene) might be a risk factor to the vitamin D (VD) nutritional status for many populations, while evidences from the Chinese Han population are...

    Authors: Ji-Chang Zhou, Yumei Zhu, Chunmei Gong, Xiongshun Liang, Xiaoying Zhou, Yuanfei Xu, Deliang Lyu, Junluan Mo, Jian Xu, Jinping Song, Xiaoling Che, Shiqiang Sun, Changhua Huang and Xiao-Li Liu

    Citation: Nutrition & Metabolism 2019 16:5

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  34. Content type: Research

    Osteoporosis is one of the world’s major medical burdens in the twenty-first century. Pharmaceutical intervention currently focusses on decelerating bone loss, but phytochemicals such as baicalein, which is a ...

    Authors: Dominik Saul, Marie Weber, Marc Hendrik Zimmermann, Robyn Laura Kosinsky, Daniel Bernd Hoffmann, Björn Menger, Stefan Taudien, Wolfgang Lehmann, Marina Komrakova and Stephan Sehmisch

    Citation: Nutrition & Metabolism 2019 16:4

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  35. Content type: Research

    Although retinol binding protein 4 (RBP4) has been implicated in insulin resistance in experimental studies, the association between RBP4 and risk of type 2 diabetes remains unclear. We assessed this associati...

    Authors: Yeli Wang, Liang Sun, Xu Lin, Jian-Min Yuan, Woon-Puay Koh and An Pan

    Citation: Nutrition & Metabolism 2019 16:3

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  36. Content type: Research

    Effective evaluation or prediction of therapy response could be helpful for treatment of chronic kidney disease (CKD), which may rely on accurate biomarkers. Acylcarnitines are involved with lipid metabolism a...

    Authors: Fang-Ying Xia, Li Zhu, Chao Xu, Qing-Qing Wu, Wan-Jia Chen, Rong Zeng and Yue-Yi Deng

    Citation: Nutrition & Metabolism 2019 16:2

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  37. Content type: Research

    Increased consumption of linoleic acid (LA, omega-6) in Western diets coupled with the pro-inflammatory and adipogenic properties of its derivatives has led to suggestions that fetal exposure to this dietary p...

    Authors: Sally A. V. Draycott, Ge Liu, Zoe C. Daniel, Matthew J. Elmes, Beverly S. Muhlhausler and Simon C. Langley-Evans

    Citation: Nutrition & Metabolism 2019 16:1

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  38. Content type: Research

    Higher dietary intake of fibers and coffee, but lower red meat intake is associated with reduced risk for type 2 diabetes in epidemiological studies. We hypothesized that a calorie-restricted diet, which is hi...

    Authors: Yanislava Karusheva, Lejla Kunstein, Alessandra Bierwagen, Bettina Nowotny, Stefan Kabisch, Jan B. Groener, Ann Kristin Fleitmann, Christian Herder, Giovanni Pacini, Klaus Strassburger, Hans-Ulrich Häring, Peter P. Nawroth, Andreas F. H. Pfeiffer, Volker Burkart, Karsten Müssig, Michael Roden…

    Citation: Nutrition & Metabolism 2018 15:90

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  39. Content type: Research

    Several studies have identified a negative association between serum glycine (Gly) levels and metabolic syndrome (MetS). However, this association has not been fully established in the elderly.

    Authors: Xianghui Li, Liang Sun, Wenduo Zhang, Hongxia Li, Siming Wang, Hongna Mu, Qi Zhou, Ying Zhang, Yueming Tang, Yu Wang, Wenxiang Chen, Ruiyue Yang and Jun Dong

    Citation: Nutrition & Metabolism 2018 15:89

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  40. Content type: Research

    Although dietary patterns have been linked to chronic diseases such as cardiovascular disease, sparse data are available for a relationship between dietary patterns and incident chronic kidney disease (CKD) in...

    Authors: Golaleh Asghari, Mehrnaz Momenan, Emad Yuzbashian, Parvin Mirmiran and Fereidoun Azizi

    Citation: Nutrition & Metabolism 2018 15:88

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  41. Content type: Research

    In a previous study, we showed that consumption of diets enriched in saturated fatty acids causes changes in alternative splicing of pre-mRNAs encoding a number of proteins in rat skeletal muscle, including th...

    Authors: Adam J. Black, Rudolf J. Schilder and Scot R. Kimball

    Citation: Nutrition & Metabolism 2018 15:87

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  42. Content type: Research

    Non-alcoholic fatty liver disease (NAFLD) is a chronic and progressive liver disease with an increased risk of morbidity and mortality. However, so far no specific pharmacotherapy has been approved. Gynostemma pe...

    Authors: Ning Jia, Xiaoyan Lin, Shizhan Ma, Shujian Ge, Shumin Mu, Chongbo Yang, Shulong Shi, Ling Gao, Jin Xu, Tao Bo and Jiajun Zhao

    Citation: Nutrition & Metabolism 2018 15:86

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  43. Content type: Review

    The current systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the effect of vitamin D supplementation on endothelial activation among patients with metabolic...

    Authors: Reza Tabrizi, Maryam Akbari, Kamran B. Lankarani, Seyed Taghi Heydari, Fariba Kolahdooz and Zatollah Asemi

    Citation: Nutrition & Metabolism 2018 15:85

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  44. Content type: Research

    It has been proved that coffee consumption was associated with a lower risk of type 2 diabetes mellitus. But the benefit effect of coffee on hyperglycemia in Chinese population was largely unknown. Besides, th...

    Authors: Fei Gao, Yinan Zhang, Sheng Ge, Huijuan Lu, Ruihua Chen, Pingyan Fang, Yixie Shen, Congrong Wang and Weiping Jia

    Citation: Nutrition & Metabolism 2018 15:84

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  45. Content type: Research

    Salvia hispanica seeds have been commonly used by people that seek healthy habits through natural foods to reduce cholesterol and triacylglycerides levels, however, the evidences that support this assumption are ...

    Authors: Cristiane Freitas Rodrigues, Willian Salgueiro, Matheus Bianchini, Juliana Cristina Veit, Robson Luiz Puntel, Tatiana Emanuelli, Cristiane Casagrande Dernadin and Daiana Silva Ávila

    Citation: Nutrition & Metabolism 2018 15:83

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  46. Content type: Research

    Consumption of fructose-rich diets has been implicated in the increasing global prevalence of metabolic syndrome (MetS). Interventions during periods of early ontogenic developmental plasticity can cause epige...

    Authors: Trevor T. Nyakudya, Emmanuel Mukwevho and Kennedy H. Erlwanger

    Citation: Nutrition & Metabolism 2018 15:82

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  47. Content type: Research

    Evidence has suggested a potential link exists between trimethylamine-N-oxide (TMAO), a choline-derived metabolite produced by gut microbiota, and some cancers, but little is known for primary liver cancer (PLC).

    Authors: Zhao-Yan Liu, Xu-Ying Tan, Qi-Jiong Li, Gong-Cheng Liao, Ai-Ping Fang, Dao-Ming Zhang, Pei-Yan Chen, Xiao-Yan Wang, Yun Luo, Jing-An Long, Rong-Huan Zhong and Hui-Lian Zhu

    Citation: Nutrition & Metabolism 2018 15:81

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