|  | Groups | P- value | |||
---|---|---|---|---|---|---|
WG (N= 7) | WSG (N= 7) | SG (N= 10) | CG (N= 14) | (time, interaction) | ||
Triacylglycerol (mg/dl) | Baseline | 100.9 ± 13.1 | 97.3 ± 11.6 | 85.0 ± 6.0 | 99.1 ± 15.0 | 0.109, 0.703 |
12 weeks | 112.7 ± 15.8 | 106.0 ± 13.1 | 99.0 ± 13.6 | 99.1 ± 12.4 | ||
Δ | +11.9 ± 15.9 | +8.7 ± 8.9 | +14.0 ± 1.0 | −0.1 ± 7.4 | ||
TC (mg/dl) | Baseline | 199.1 ± 9.8 | 224.7 ± 13.6 | 201.7 ± 6.8 | 212.6 ± 5.7 | 0.001, 0.012 |
12 weeks | 235.3 ± 10.7†| 237.6 ± 11.4†| 217.5 ± 7.3†| 214.6 ± 7.1 | ||
Δ | +36.1 ± 8.1‡ | +12.9 ± 5.2 | +15.8 ± 6.7 | +2.1 ± 6.1 | ||
HDL-C (mg/dl) | Baseline | 61.6 ± 4.0 | 64.7 ± 7.6 | 56.3 ± 3.4 | 63.5 ± 5.35 | 0.081, 0.165 |
12 weeks | 70.6 ± 6.6†| 63.7 ± 7.0 | 59.1 ± 3.7 | 63.8 ± 4.15 | ||
Δ | +9.0 ± 3.4 | −1.0 ± 3.0 | +2.8 ± 1.3 | +0.3 ± 3.2 | ||
LDL-C (mg/dl) | Baseline | 115.0 ± 7.1 | 132.6 ± 11.2 | 119.4 ± 6.3 | 118.7 ± 5.4 | 0.004, 0.122 |
12 weeks | 135.0 ± 9.1 | 140.3 ± 9.1 | 125.6 ± 7.6 | 119.4 ± 5.8 | ||
Δ | +20.0 ± 8.4 | +7.7 ± 5.5 | +6.2 ± 5.5 | +0.7 ± 3.8 | ||
Glucose (mg/dl) | Baseline | 96.9 ± 2.8 | 110.0 ± 8.4 | 91.1 ± 1.5 | 90.2 ± 1.2 | 0.992, 0.098 |
12 weeks | 100.3 ± 2.9 | 106.1 ± 8.8 | 89.4 ± 2.2 | 92.8 ± 1.1†| ||
Δ | +3.4 ± 2.7 | −3.9 ± 3.1 | −1.7 ± 2.5 | +2.6 ± 1.2 | ||
Insulin (pmol/L) | Baseline | 26.1 ± 5.4 | 22.6 ± 4.6 | 17.6 ± 3.2 | 22.4 ± 1.3 | 0.021, 0.374 |
12 weeks | 26.5 ± 5.4 | 33.5 ± 8.4 | 24.7 ± 2.3 | 24.9 ± 2.1 | ||
Δ | +0.3 ± 7.5 | +10.9 ± 5.8 | +7.1 ± 3.7 | +2.6 ± 1.7 | ||
HbA1c (%) | Baseline | 5.37 ± 0.11 | 5.54 ± 0.27 | 5.10 ± 0.09 | 5.11 ± 0.10 | 0.001, 0.823 |
12 weeks | 5.21 ± 0.08 | 5.34 ± 0.27†| 5.00 ± 0.07†| 4.97 ± 0.04 | ||
Δ | −0.16 ± 0.06 | −0.20 ± 0.02 | −0.10 ± 0.04 | −0.14 ± 0.08 | ||
C-peptide (pmol/L) | Baseline | 374.4 ± 50.9 | 366.9 ± 40.5 | 369.9 ± 31.5 | 360.8 ± 29.1 | 0.001, 0.578 |
12 weeks | 470.1 ± 71.3 | 492.0 ± 99.2 | 427.6 ± 36.6 | 415.8 ± 31.0†| ||
Δ | +95.6 ± 66.1 | +125.1 ± 67.9 | +57.7 ± 30.8 | +55.0 ± 13.1 | ||
sE-selectin (ng/ml) | Baseline | 41.6 ± 7.1 | 48.9 ± 8.7 | 41.1 ± 2.9 | 39.3 ± 3.5 | 0.001, 0.442 |
12 weeks | 47.4 ± 7.1 | 51.3 ± 8.2 | 44.0 ± 2.9 | 46.2 ± 3.7†| ||
Δ | +5.8 ± 3.7 | +2.4 ± 1.6 | +2.9 ± 2.2 | +6.9 ± 2.0 | ||
sVCAM-1 (ng/ml) | Baseline | 748.3 ± 56.8 | 689.6 ± 43.9 | 603.4 ± 24.2 | 692.5 ± 47.8 | 0.019, 0.060 |
12 weeks | 771.8 ± 66.5 | 692.6 ± 45.8 | 610.8 ± 26.1 | 760.3 ± 59.0†| ||
Δ | +23.5 ± 19.1 | +3.0 ± 27.2 | +7.4 ± 16.3 | +67.8 ± 17.5 |