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Table 5 Estimates of D9D activity according to genotype for each SCD1 SNP in Caucasians

From: Plasma concentration of cis 9trans 11 CLA in males and females is influenced by SCD1 genetic variations and hormonal contraceptives: a cross-sectional study

  [18:2c9t11/18:1 t11] in males [18:2c9t11/18:1 t11] in females
MM Mm mm P-value MM Mm mm P-value
rs10883463 1.077 ± 0.036a 0.769 ± 0.048b - <0.01* 1.206 ± 0.036 1.244 ± 0.061 1.505 ± 0.170 0.75
rs17669878 1.079 ± 0.070 0.977 ± 0.040 1.064 ± 0.076 0.23 1.248 ± 0.041 1.195 ± 0.050 1.207 ± 0.074 0.72
rs2060792 1.015 ± 0.037 0.998 ± 0.061 1.215 ± 0.179 0.62 1.251 ± 0.053 1.175 ± 0.036 1.229 ± 0.088 0.58
rs3071 1.037 ± 0.052 1.024 ± 0.046 0.913 ± 0.051 0.78 1.202 ± 0.031 1.224 ± 0.059 1.238 ± 0.105 0.87
rs3793766 1.003 ± 0.036 1.083 ± 0.078 1.200 0.59 1.217 ± 0.035 1.209 ± 0.057 1.084 ± 0.391 0.94
rs3793767 0.939 ± 0.042 1.043 ± 0.051 1.111 ± 0.097 0.25 1.178 ± 0.043 1.252 ± 0.052 1.200 ± 0.054 0.81
rs490726 1.073 ± 0.042 0.960 ± 0.053 0.856 ± 0.344 0.23 1.215 ± 0.041 1.217 ± 0.046 1.229 ± 0.107 0.99
rs522951 1.044 ± 0.046 1.011 ± 0.050 1.019 ± 0.081 0.78 1.125 ± 0.055 1.252 ± 0.049 1.237 ± 0.048 0.42
rs569184 1.010 ± 0.036 1.060 ± 0.079 1.200 0.72 1.223 ± 0.035 1.198 ± 0.054 0.637 ± 0.055 0.38
rs575338 1.024 ± 0.042 1.024 ± 0.045 1.003 ± 0.155 0.99 1.193 ± 0.029 1.291 ± 0.098 1.188 ± 0.084 0.44
  1. Results of analysis of 10 SNPs from SCD1 for associations with D9D activity index [182c9t11:181 t11]. Different letters (a or b) denote values that are significantly different between groups. P-values were determined using linear regression models which were adjusted for BMI, age, % of Total Energy from Dietary Fat and physical activity. Caucasian Males: n = 113; Caucasian females: n = 298; Asian Males: n = 98; Asian Females: n = 277. Abbreviations: D9D, delat-9-desaturase; M, major; m, minor; ‘-’ indicates that no subjects with this genotype were present in this population.