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Table 1 Effect of ATP supplementation on muscle strength and power in participants performing a 12 week weight training regimen. a

From: Effects of oral adenosine-5′-triphosphate supplementation on athletic performance, skeletal muscle hypertrophy and recovery in resistance-trained men

 

Week of Study

 
 

0

4

8

9

10

12

p-valueb

Squat, kg

       

Placebo

145.2 ± 10.2

151.6 ± 11.0

156.4 ± 11.6

150.7 ± 10.4

147.2 ± 10.7

151.3 ± 10.3

 

ATP

146.1 ± 5.8

155.2 ± 7.7

160.7 ± 7.6

159.0 ± 6.1#

158.6 ± 6.9#

165.3 ± 8.3#

<0.001

Bench Press, kg

       

Placebo

115.2 ± 9.4

119.3 ± 9.4

121..4 ± 9.3

113.4 ± 7.2

115.7 ± 8.0

119.3 ± 8.7

 

ATP

117.2 ± 5.5

122.1 ± 5.0

124.5 ± 5.2

120.0 ± 4.8

121.2 ± 5.5

124.2 ± 5.4

0.65

Deadlift, kg

       

Placebo

169.8 ± 11.0

177.0 ± 10.7

182.5 ± 10.7

173.2 ± 10.8

174.8 ± 8.1

182.0 ± 9.2

 

ATP

176.2 ± 4.9

189.2 ± 5.9

200.3 ± 7.4#

193.4 ± 6.4#

193.8 ± 8.3#

205.2 ± 6.9#

0.002

Total Strength, kg

      

Placebo

430.2 ± 28.1

448.0 ± 28.9

460.2 ± 29.6

437.3 ± 26.1

437.6 ± 25.1

452.6 ± 25.9

 

ATP

439.4 ± 14.9

466.5 ± 17.1

485.6 ± 18.1#

472.4 ± 15.2#

473.6 ± 18.3#

494.7 ± 17.9#

<0.001

Wingate Peak Power, Watts

      

Placebo

882.2 ± 54.1

930.3 ± 55.7

985.3 ± 64.7

922.9 ± 61.9

939.9 ± 65.7

977.4 ± 66.5

 

ATP

882.8 ± 27.0

960.9 ± 36.1

1003.5 ± 40.4

964.2 ± 38.0

974.7 ± 39.8

1011.9 ± 42.4

0.48

Vertical Jump power, Watts

      

Placebo

5318 ± 410

5711 ± 439

5918 ± 443

5697 ± 436

5626 ± 431

5932 ± 452

 

ATP

5185 ± 203

5618 ± 213

5954 ± 202#

5838 ± 218#

5827 ± 208#

5981 ± 207#

<0.001

  1. aMean ± SEM for n = 11 ATP (400 mg ATP/d taken 30 min prior to exercise) and n = 10 placebo supplemented participants.
  2. bProbability of treatment by time difference between the placebo and the ATP treatments over the 12-week study. The mixed model ANOVA in SAS® was used with the main effects of treatment, time and treatment by time, with the value for week 0 used as a covariate.
  3. #Significantly different than corresponding placebo, t-test (p < 0.05).