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Table 2 Effect of ATP supplementation on body composition and Quadriceps thickness in participants performing a 12 week weight training regimen. a

From: Effects of oral adenosine-5′-triphosphate supplementation on athletic performance, skeletal muscle hypertrophy and recovery in resistance-trained men

  Week of Study  
  0 4 8 12 p-valueb
Weight, kg      
Placebo 87.4 ± 4.3 88.3 ± 4.6 88.7 ± 4.8 87.7 ± 4.7  
ATP 85.7 ± 1.7 86.9 ± 2.0 87.0 ± 2.0 87.0 ± 2.1 0.49
DXA LBM, kg      
Placebo 68.5 ± 2.6 70.0 ± 2.3 71.2 ± 2.4 70.5 ± 2.4  
ATP 67.7 ± 2.0 70.1 ± 1.9 71.4 ± 2.0# 71.7 ± 1.9# .009
DXA Fat,%      
Placebo 21.0 ± 1.1 19.8 ± 1.6 18.6 ± 1.9 18.6 ± 1.7  
ATP 19.5 ± 1.8 18.1 ± 1.8 16.6 ± 1.6 16.0 ± 1.5 0.76
Quad, mm      
Placebo 50.2 ± 2.1 52.2 ± 2.3 52.6 ± 2.4 52.7 ± 2.4  
ATP 50.9 ± 0.9 53.4 ± 1.3 54.8 ± 1.7 55.8 ± 1.8# 0.02
  1. aMean ± SEM for n = 11 ATP (400 mg ATP/d taken 30 min prior to exercise) and n = 10 placebo supplemented participants.
  2. bProbability of treatment by time difference between the placebo and the ATP treatments over the 12-week study. The mixed model ANOVA in SAS® was used with the main effects of treatment, time and treatment by time, with the value for week 0 used as a covariate.
  3. #Significantly different than corresponding placebo, t-test (p < 0.05).