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Table 4 Summary of the effect of THC on performance

From: The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance

TETRAHYDROCANNABINOL
WADA status: the International Olympic Committee included cannabis in the banned substance list beginning in 1989 and since 2004 the World Anti-Doping Agency has prohibited its use for all sports competition [[163]]
Acute effect Effect on performance THC dose Reference
Resting heart rate and both systolic/diastolic blood pressure were significantly elevated at rest Physical work capacity at a heart rate of 170 decreased by 25% compared to placebo 18.2 mg of Δ9-THC Steadward and Singh [154]
Induced tachycardia at rest VE, VO2 and VCO2 were increased above control at ≥50% max effort; Small, but significant reduction in maximal exercise duration; tachycardia up to 80% of maximum effort and during recovery 7 mg/kg marijuana (containing 1.7% Δ9-THC) Renaud and Cormier [155]
Increased heart rate and the rate-pressure product at rest No effect on blood pressure, ventilation or oxygen uptake during submaximal exercise (15 min at 50% of VO2max); increased heart rate and the rate-pressure product during recovery Smoking 7.5 mg of Δ9-THC Avakian et al. [156]