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Table 1 Clinical characteristics of study participants at fasting

From: Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals

  Controls Type 1 diabetes p
Age (yrs) 38.2 ± 10.3 42.5 ± 9.4 ns
Sex (M/F) 18/16 16/21 ns
Duration of diabetes (yrs) - 26 ± 13 -
BMI (kg/m 2 ) 25.2 ± 4.2 26.1 ± 3.6 ns
Systolic blood pressure (mmHg) 129 ± 14 133 ± 17 ns
Diastolic blood pressure (mmHg) 77 ± 10 77 ± 8 ns
HbA 1c (%) (mmol/mol) 5.3 ± 0.3 (34 ± 3.3) 8.0 ± 1.3 (64 ± 14.2) <0.001
eGFR (ml/min/1.72 m 2 ) 102 (93–110) 101 (94–114) ns
AER (mg/24 h) 3.4 (2.4–5.2) 7.0 (3.8–13.4) 0.001
Blood glucose (mmol/l) 4.9 ± 0.6 8.7 ± 3.4 <0.001
Cholesterol (mmol/l) 4.7 ± 0.7 4.6 ± 0.7 ns
Triglycerides (mmol/l) 1.0 ± 0.3 0.9 ± 0.5 ns
HDL-chol (mmol/l) 1.3 (1.1–1.7) 1.6 (1.3–1.8) ns
LDL-chol (mmol/l) 2.8 ± 0.7 2.6 ± 0.7 ns
ApoB-100 (mg/dL) 83 (73–93) 72 (66–87) ns
ApoA1 (mg/dL) 138 (123–158) 153 (132–162) ns
ApoB-48 (mg/dL) 3.8 (2.7–5.4) 5.0 (3.7–8.8) 0.014
High-sensitive CRP (mg/l) 1.0 (0.2–2.7) 1.5 (0.3–5.4) ns
Interleukine-6 (pg/ml) 1.2 (0.8–2.0) 1.5 (0.5–3.5) ns
LPS (EU/ml) 0.82 (0.57–1.43) 0.90 (0.52–1.24) ns
  1. Data at fasting are presented as mean ± SD or median (25th-75th quartile). AER – albumin excretion rate, eGFR – estimated glomerular filtration rate.