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Table 1 Effects of vitamin A supplementation on biometric parameters in WNIN/Ob rats

From: Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats

Parameters

Lean

Obese

 

AI

AII

AIII

AIV

BI

BII

BIII

BIV

Initial body wt. (g)

352 ± 13.3a

374 ± 8.2a

351 ± 21.8a

362 ± 24.9a

628 ± 48.3b

594 ± 36.4b

574 ± 27.9b

591 ± 12.9b

Final body wt. (g)

424 ± 19.8a

455 ± 7.1a

441 ± 19.2a

454 ± 13.3a

926 ± 56.2b

883 ± 38.9bc

811 ± 33.4cd

778 ± 23.8d

Body wt. gain (g)

72 ± 18.9a

80 ± 10.1a

90 ± 25.1a

92 ± 15.9a

298 ± 22.1b

288 ± 10.9bc

237 ± 20.8cd

189 ± 17.2d

Food intake (g/day)

18.9 ± 0.57a

17 .4 ± 0.68a

19.4 ± 2.15a

18.8 ± 0.86a

27.9 ± 0.82b

29.3 ± 1.06b

28.1 ± 1.33b

26.8 ± 0.60b

Lean body mass (g)

361 ± 14.9a

398 ± 8.3a

389 ± 15.0a

402 ± 11.1a

410 ± 26.9a

399 ± 17.6a

376 ± 15.1a

362 ± 9.1a

Total body fat (g)

63 ± 5.6a

57 ± 3.2a

52 ± 5.6a

52 ± 4.8a

516 ± 30.8b

481 ± 15.5b

435 ± 18.5c

416 ± 15.3c

Fat%*

14.6 ± 0.75a

12.6 ± 0.77b

11.7 ± 0.90b

11.4 ± 0.84b

55.8 ± 0.69c

54.7 ± 0.40cd

53.7 ± 0.22d

53.4 ± 0.44d

rWAT ϕ

1.2 ± 0.07a

1.3 ± 0.23a

1.1 ± 0.19a

1.5 ± 0.19a

9.4 ± 1.02b

8.1 ± 0.19bd

7.6 ± 1.22cd

6.4 ± 0.45c

eWAT@

0.8 ± 0.22ac

0.7 ± 0.06ac

0.6 ± 0.05ac

0.7 ± 0.08ac

1.5 ± 0.26b

1.4 ± 0.35bd

0.9 ± 0.08cd

1.0 ± 0.12abc

Rectal temperature (°C)

37.6 ± 0.03ae

37.6 ± 0.31ae

37.6 ± 0.31ae

37.6 ± 0.22ae

36.0 ± 0.19b

37.7 ± 0.18a

38.3 ± 0.21cd

37.7 ± 0.12ce

  1. Five-month-old male lean (A) and obese (B) rats were fed vitamin A at a dose of 2.6 (I), 26 (II), 52 (III) and 129 (IV) mg/kg diet for a period of 20 weeks. AI served as the control group for lean phenotype, while BI was control group for obese phenotype. Data are mean ± SE (n=8 for AI, AII, AIII, AIV; n=7 for BI, BII, BIV; n=6 for BIII). LBM, lean body mass; FAT%, fat percentage; eWAT, epididymal WAT; rWAT, retroperitoneal WAT.
  2. a–e Mean values within a row not sharing a common superscript were significantly different by oneway ANOVA and LSD post hoc comparison (P < 0.05). * Total body fat expressed as a percentage of body weight. ϕMass of rWAT expressed as a percentage of body weight. @ Mass of eWAT expressed as a percentage of body weight.