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Table 1 Effects of vitamin A supplementation on biometric parameters in WNIN/Ob rats

From: Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats

Parameters Lean Obese
  AI AII AIII AIV BI BII BIII BIV
Initial body wt. (g) 352 ± 13.3a 374 ± 8.2a 351 ± 21.8a 362 ± 24.9a 628 ± 48.3b 594 ± 36.4b 574 ± 27.9b 591 ± 12.9b
Final body wt. (g) 424 ± 19.8a 455 ± 7.1a 441 ± 19.2a 454 ± 13.3a 926 ± 56.2b 883 ± 38.9bc 811 ± 33.4cd 778 ± 23.8d
Body wt. gain (g) 72 ± 18.9a 80 ± 10.1a 90 ± 25.1a 92 ± 15.9a 298 ± 22.1b 288 ± 10.9bc 237 ± 20.8cd 189 ± 17.2d
Food intake (g/day) 18.9 ± 0.57a 17 .4 ± 0.68a 19.4 ± 2.15a 18.8 ± 0.86a 27.9 ± 0.82b 29.3 ± 1.06b 28.1 ± 1.33b 26.8 ± 0.60b
Lean body mass (g) 361 ± 14.9a 398 ± 8.3a 389 ± 15.0a 402 ± 11.1a 410 ± 26.9a 399 ± 17.6a 376 ± 15.1a 362 ± 9.1a
Total body fat (g) 63 ± 5.6a 57 ± 3.2a 52 ± 5.6a 52 ± 4.8a 516 ± 30.8b 481 ± 15.5b 435 ± 18.5c 416 ± 15.3c
Fat%* 14.6 ± 0.75a 12.6 ± 0.77b 11.7 ± 0.90b 11.4 ± 0.84b 55.8 ± 0.69c 54.7 ± 0.40cd 53.7 ± 0.22d 53.4 ± 0.44d
rWAT ϕ 1.2 ± 0.07a 1.3 ± 0.23a 1.1 ± 0.19a 1.5 ± 0.19a 9.4 ± 1.02b 8.1 ± 0.19bd 7.6 ± 1.22cd 6.4 ± 0.45c
eWAT@ 0.8 ± 0.22ac 0.7 ± 0.06ac 0.6 ± 0.05ac 0.7 ± 0.08ac 1.5 ± 0.26b 1.4 ± 0.35bd 0.9 ± 0.08cd 1.0 ± 0.12abc
Rectal temperature (°C) 37.6 ± 0.03ae 37.6 ± 0.31ae 37.6 ± 0.31ae 37.6 ± 0.22ae 36.0 ± 0.19b 37.7 ± 0.18a 38.3 ± 0.21cd 37.7 ± 0.12ce
  1. Five-month-old male lean (A) and obese (B) rats were fed vitamin A at a dose of 2.6 (I), 26 (II), 52 (III) and 129 (IV) mg/kg diet for a period of 20 weeks. AI served as the control group for lean phenotype, while BI was control group for obese phenotype. Data are mean ± SE (n=8 for AI, AII, AIII, AIV; n=7 for BI, BII, BIV; n=6 for BIII). LBM, lean body mass; FAT%, fat percentage; eWAT, epididymal WAT; rWAT, retroperitoneal WAT.
  2. a–e Mean values within a row not sharing a common superscript were significantly different by oneway ANOVA and LSD post hoc comparison (P < 0.05). * Total body fat expressed as a percentage of body weight. ϕMass of rWAT expressed as a percentage of body weight. @ Mass of eWAT expressed as a percentage of body weight.