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Table 2 Effects of vitamin A supplementation on retinol levels in WNIN/Ob rats

From: Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats

Parameters

Lean

Obese

 

AI

AII

AIII

AIV

BI

BII

BIII

BIV

Serum retinol (μg/dL)

28 ± 1.4a

28 ± 1.3a

26 ± 2.0a

29 ± 3.4a

40 ± 1.6b

41 ± 2.5b

46 ± 3.9b

43 ± 5.7b

Liver retinol (μg/g tissue)

967 ± 386a

3795 ± 211bc

4556 ± 465bc

9842 ± 1151d

375 ± 60a

2840 ± 221b

5031 ± 239c

8133 ± 883d

rWAT retinol (μg/g tissue)

4 ± 1.2ac

14 ± 3.0ade

19 ± 1.5de

41 ± 7.7b

2 ± 0.3c

11 ± 0.9acd

24 ± 3.4e

48 ± 5.6b

  1. Five-month-old male lean (A) and obese (B) rats were fed vitamin A at a dose of 2.6 (I), 26 (II), 52 (III) and 129 (IV) mg/kg diet for a period of 20 weeks. AI served as the control group for lean phenotype, while BI was control group for obese phenotype. Data are mean ± SE (n=8 for AI, AII, AIII, AIV; n=7 for BI, BII, BIV; n=6 for BIII). rWAT, retroperitoneal WAT.
  2. a–e Mean values within a row not sharing a common superscript were significantly different by oneway.
  3. ANOVA and LSD post hoc comparison (P < 0.05).