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Table 2 Effects of vitamin A supplementation on retinol levels in WNIN/Ob rats

From: Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats

Parameters Lean Obese
  AI AII AIII AIV BI BII BIII BIV
Serum retinol (μg/dL) 28 ± 1.4a 28 ± 1.3a 26 ± 2.0a 29 ± 3.4a 40 ± 1.6b 41 ± 2.5b 46 ± 3.9b 43 ± 5.7b
Liver retinol (μg/g tissue) 967 ± 386a 3795 ± 211bc 4556 ± 465bc 9842 ± 1151d 375 ± 60a 2840 ± 221b 5031 ± 239c 8133 ± 883d
rWAT retinol (μg/g tissue) 4 ± 1.2ac 14 ± 3.0ade 19 ± 1.5de 41 ± 7.7b 2 ± 0.3c 11 ± 0.9acd 24 ± 3.4e 48 ± 5.6b
  1. Five-month-old male lean (A) and obese (B) rats were fed vitamin A at a dose of 2.6 (I), 26 (II), 52 (III) and 129 (IV) mg/kg diet for a period of 20 weeks. AI served as the control group for lean phenotype, while BI was control group for obese phenotype. Data are mean ± SE (n=8 for AI, AII, AIII, AIV; n=7 for BI, BII, BIV; n=6 for BIII). rWAT, retroperitoneal WAT.
  2. a–e Mean values within a row not sharing a common superscript were significantly different by oneway.
  3. ANOVA and LSD post hoc comparison (P < 0.05).