Figure 2

Effects of dietary naringenin on adiposity, plasma adipokines, and adipose tissue gene expression. At week 19, MRI analysis was performed in a subset of mice (n = 6/group) to measure percentage of total body fat and percentage of two adipose tissue depots, intra-abdominal and subcutaneous adipose tissues (A). Fasting plasma leptin and adiponectin in the CON (n = 6) and NAR (n = 5-6) groups were measured at the end of study at 22 weeks (B). Panel (C) shows representative coronal MRI views from each group. Effects of dietary naringenin on the mRNA levels of genes in perigonadal adipose tissue (D) and in subcutaneous adipose tissue (E) are shown (CON, n = 6-8; NAR, n = 10). Values are presented as mean ± SEM. Significance between groups was determined by Student’s t test. ^#P < 0.05 compared CON with NAR.