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Table 1 Ratio of RANKL/OPG in Osteoclasts and Osteoblasts in Rats on a .04% NR Diet

From: Immunolocalization of RANKL is Increased and OPG Decreased During Dietary Magnesium Deficiency in the Rat

 

Osteoclast

Osteoblast

Day 1 Control

1

0.44

Day 1 .04% NR

0.4

.046

Day 3 Control

0.6

0.55

Day 3 .04% NR

0.51

0.24

Day 8 Control

1

0.44

Day 8 .04% NR

0.25

0.33

Day 15 Control

1.25

0.29

Day 15 .04% NR

0.79

0.38

Day 22 Control

0.65

0.05

Day 22 .04% NR

0.12

0.25

Day 28 Control

.029

0.12

Day 28 .04% NR

.052

0.16

Day 84 Control

.096

0.14

Day 84 .04% NR

0.256

1.66

  1. As shown in Table 1 there is no apparent excess of RANKL relative to OPG in rats on a diet containing .04% of NR until after day 22.