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Table 1 Ratio of RANKL/OPG in Osteoclasts and Osteoblasts in Rats on a .04% NR Diet

From: Immunolocalization of RANKL is Increased and OPG Decreased During Dietary Magnesium Deficiency in the Rat

  Osteoclast Osteoblast
Day 1 Control 1 0.44
Day 1 .04% NR 0.4 .046
Day 3 Control 0.6 0.55
Day 3 .04% NR 0.51 0.24
Day 8 Control 1 0.44
Day 8 .04% NR 0.25 0.33
Day 15 Control 1.25 0.29
Day 15 .04% NR 0.79 0.38
Day 22 Control 0.65 0.05
Day 22 .04% NR 0.12 0.25
Day 28 Control .029 0.12
Day 28 .04% NR .052 0.16
Day 84 Control .096 0.14
Day 84 .04% NR 0.256 1.66
  1. As shown in Table 1 there is no apparent excess of RANKL relative to OPG in rats on a diet containing .04% of NR until after day 22.