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Table 2 Percent Difference in Immunocytochemical Staining for RANKL and OPG

From: Immunolocalization of RANKL is Increased and OPG Decreased During Dietary Magnesium Deficiency in the Rat

  25% NR
  Osteoclast Osteoblast
  RANKL OPG RANKL OPG
2 Month 25% vs Control 86 -150 -10 -113
4 Month 25% vs Control -16 -160 -232 -160
6 Month 25% vs Control 116 -700 -82 -700
  1. As shown in Table 2, the percent relative difference in immunocytochemical staining in rats on a diet containing 25% NR Mg for RANKL in osteoclasts was increased at 2 and 6 months and decreased in osteoblasts. Staining for OPG was markedly decreased in both cell lines at all time points compared to control.