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Table 1 Rates of hepatic glycogen changes and ATP changes (nmol·min-1·g-1 of liver ww).

From: Insulin induces a positive relationship between the rates of ATP and glycogen changes in isolated rat liver in presence of glucose; a 31P and 13C NMR study

 

Experimental conditions

 

Control (KHB)

Group A,

n = 7

G 6 mM

Group B,

n = 8

G 30 mM

Group C,

n = 8

Insulin

Group D,

n = 5

Insulin + G 6 mM

Group E,

n = 5

Insulin + G 30 mM

Group F,

n = 5

GLYCOGEN

-387 ± 73

(a) -64 ± 109*

p = 0.02 vs control

(b) -474 ± 102

NS vs control

(a) +52 ± 95**

p = 0.003 vs control

(b) -277 ± 80

NS vs control

-431 ± 29

NS vs control

-29 ± 73

p < 0.003 vs insulin NS vs G6(a)

+139 ± 47

p < 0.00001 vs insulin

p = 0.015 vs G30(a)

ATP

-7.28 ± 0.76

-10.14 ± 1.61

NS vs control

-5.98 ± 1.22

NS vs control

-8.06 ± 1.22

NS vs control

-3.38 ± 0.17

p = 0.03 vs insulin

p = 0.01 vs G6

-0.10 ± 0.42

p = 0.003 vs insulin

p = 0.006 vs G30

  1. 100% glycogen = 73 ± 8.5 μmol glycosyl units·g-1 of liver ww; 100% ATP = 2.60 ± 0.65 μmol·g-1 of liver ww. The rates of glycogen changes were biphasic in group B and C; the first phase (a) lasted *20 min or **60 min. Mean ± SEM.