Alterations in glucose homeostaisis in PEPCK-C-/- and control mice during the perinatal period. Panel A Hypoglycemia in PEPCK-C-/- mice. The concentration of blood glucose was measured in mice at one, two and three days after birth. The results are expressed as the mean ± S.E. for from three to six animals. Panel B. Increased mobilization of hepatic glycogen. The hepatic glycogen level was analyzed at the age of fetal day 19 (day -1) and neonatal day (day +2). The results are expressed as the mean ± S.E. for three animals in each group.